摘要
目的 观察白细胞过滤器过滤库存全血或红细胞前后血液质量变化 ,及其防止非溶血性输血反应的临床效果。方法 将全血或红细胞用白细胞过滤器滤除白细胞 ,取过滤前后的血液标本进行质量检测 ,过滤后的去白细胞血液 ,应用于以往有输血反应的 2 8例患者 ,并观察临床非溶血性输血反应情况。结果 用白细胞过滤器过滤后 ,白细胞滤除率 99.6 % ,血小板滤除率 77.0 % ,红细胞回收率 96 .3 % ,凝血因子、红细胞脆性无显著变化 (P>0 .0 5 ) ,非溶血性输血反应发生率为 1 .7% ,较应用前非溶血性输血反应发生率为 41 %明显降低 ,两者比较有显著性差异 (χ2 =5 5 .3 8,P<0 .0 1 )。结论 说明白细胞过滤器前后血液质量没有明显变化 。
Objective To observe the changes of blood quality before and after being filtered by white cell filter and observe the clinical effect of white cell filter which prevent the non hemolytic blood transfusion reactions. Methods The white blood cells were removed by white cell filter from whole or packed red blood cell.The blood quality was detected and the type of filtered white cell blood was used into 28 patients who had transfusion in the past.Then observed the non hemolytic blood transfusion reactions.Results The removing rate of white cell was 99.6%,and platelets 77.0%,the retrieving rate was 96.3% .There were significant difference erythrocyte fragility test and thrombin factor ( P >0.05).Reaction rate of non hemolytic blood transfusion reactions was 1.7% after using white cell filter and it was 41% before.There was significant difference (χ 2 =55 38, P <0 01) Conclusion White cell filter can significanty reduce the incidence of clinical non hemolytic blood transfusion reactions.
出处
《陕西医学检验》
2001年第4期5-6,共2页
Shaanxi Journal of Medical Laboratory Sciences