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白癜风的细胞免疫研究进展 被引量:11

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摘要 白癜风的发病存在细胞免疫机制。目前研究显示:白癜风的细胞免疫学证据主要表现在外周血CD4+细胞下降,而皮损局部浸润却以CD8+为主。这一现象可能和CD8+ 细胞需要依赖于CD4+ 细胞先活化的经典途径有关;但是局部CD8+ 细胞的某些分布模式提示存在CD8+ 和黑素细胞之间的直接作用的可能;另外,有关白癜风样白斑的研究亦将为之提供线索和启发。
作者 鲁严 朱文元
出处 《国外医学(皮肤性病学分册)》 2001年第6期355-358,共4页 Foreign Medical Sciences(Section of Dermatology and Venereology)
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  • 1Nordlund JJ.Howanitz N.The Pignentary System:Physiology and Pathology.1 st ed.New York:Oxford University Press,1998.656-657.
  • 20rtonne JP.Alario A.T and B lymmphocytes in vitiligo.Arch Dermatol Res.1978.261(2):147-151.
  • 3Mahmoud F,Abul H.al-Saleh Q,et al.Peripherar T-cell activation in non-segmental vitiligo.J Dematol,1998,25(10):637-640.
  • 4Mozzanica N.Frigerio U,Finzi AF.et al.T cell subpopulations in vitili go:a chronobiologic study.J Am Acad Dermatol,1990,22(2 Pt 1):223-230.
  • 5Grimes PE.Ghoneum M.Stockton T,et al.Z cell profiles in vitiligo.JAm Acad Dermatol,1986,14(2 Pt 1):196-201.
  • 6Honda Y.Okubo Y,Koga M.Relationship between levels of soluble in-terleukin-2 receptors and the types and activity of vitiligo.J Dermatol,1997.24(9):561-563.
  • 7Taher-Uz-Zaman.Begun S,Waheed MA.In vitro assessment of 'T'lymphocyte functioning in vitiligo.Support for autoimmune hypothesis concerning the disease.Acta Derm Venereol,1992,72(4):266-267.
  • 8Hann SK.Park YK.Chung KY,et al.Peripheral blood lymphocyte im- balance in Koreans with active vitiligo.Int J Dermatol,1993,32(4):286-289.
  • 90gg GS.Rod Dunbar P,Romero P,et al.High frequency of skin-homing melanocyte-specific cvtotoxic T lymphocytes in autoimmune vitiligo.J ExpMed.1998.188(6):1203-1208.
  • 10Le Poole IC,van den Wijngaard RM,Westerhof W,et al.Presence of Tcells and macrophages in inflammatory vitiligo skin parallels melanocyte disappearance.Am J Pathol,1996,148(4):1219-1228.

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