摘要
目的 :了解 β 内酰胺类抗生素使用现状 ,为临床合理用药提供资料及依据。方法 :分别统计某综合医院检验科细菌室药敏试验检出菌对 13种β 内酰胺类抗生素耐药性试验结果和 15种常用β 内酰胺类抗生素的用药频度 (DDDs) ,结合药敏结果及DDDs值 ,对 β 内酰胺类抗生素使用现状进行综合分析。结果 :青霉素类抗生素的耐药率极高 ,β 内酰胺酶抑制剂 +β 内酰胺类抗生素的联合制剂、碳青霉烯类等非典型 β 内酰胺类抗生素耐药率低。青霉素、氨苄西林、头孢唑林、舒他西林的用药频度 (DDDs)分别列 1～ 4位。结论 :青霉素类抗生素存在不合理应用 ,部分头孢菌素类抗生素、β 内酰胺酶抑制剂、碳青霉烯类抗生素应用较为合理。
Objective: To know the using current status of β lactams antibiotics, the data and foundation were provided for clinical rational drug use. Method: The resistance test results of the isolated bacteria against 13 β lactams antibiotics and the DDDs of 15 common β lactams antibiotics were counted respectively. The current status of used β lactam antibiotics combined with medical sensitivity result were analysed comprehensively. Result: The resistant rate of penicillins antibiotics was very high, that of β lactamase inhibitor plus β lactams, antibiotis carbapenaems(non type of β lactams antibiotics) was low , DDDs of penicillin, ampicillin, cefazolin, and sultamicillin were arranged at 1 4 position, respectively. Conclusion: Penicillins antibiotics exsisted non national application, the partial cephalosporins, β lactamase inhibitor, carbapenaems antibiotics have a more national application.
出处
《药物流行病学杂志》
CAS
2001年第4期200-202,共3页
Chinese Journal of Pharmacoepidemiology
