摘要
目的 对脑胰岛素的含量进行确认 ,探讨脑胰岛素的来源。方法 用放射免疫法测定Wistar大鼠各脑区胰岛素含量及血浆中胰岛素的含量。结果 嗅球胰岛素含量最高 ,嗅球、海马、下丘脑胰岛素含量明显高于血浆胰岛素含量。脑胰岛素含量由高到低依次为 :嗅球、海马、下丘脑、桥脑、中脑、延髓、大脑皮层、小脑。
Objective To affirm brain insulin concentration, and study its source.Methods Using the radioimmunoassay, the insulin concentrations were measured in plasma and different parts of Wistar rats brain.Results Olfactory bulbs insulin concentration was the highest. The insulin concentration in olfactory bulb, hippocampus, hypothalamus was higher than that in plasma. The insulin concentrations in different part of brain, from high to low were: olfactory bulb>hippocampus>hypothalamus>pons>midbrain>medulla>cerebral cortex>cerebellum.Conclusion Brain probably produce insulin by itself.
