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海洛因白质脑病的CT与MRI诊断 被引量:12

CT and MRI diagnosis of heroininduced leukoencephalopathy
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摘要 目的 研究CT与MRI对烫吸海洛因蒸汽引起海绵状白质脑病的特征性影像学诊断价值。方法 对 2例烫吸海洛因引起的海绵状白质脑病的患者进行了临床和CT与MRI观察 ,查阅中外文献 ,对该病影像学特征结合临床表现、病理组织改变进行总结与讨论。结果  2例患者以小脑性共济失调、智力减退为主要临床表现 ,CT显示对称性分布的小脑白质、大脑白质为主的低密度改变 ;MRI显示对称性分布的小脑齿状核 ,大脑半球半卵圆中心、双基底节内囊、中脑、桥脑白质纤维为主的高信号改变。结论 烫吸海洛因引起海绵状白质脑病的CT与MRI影像学改变具有特征性 ,能为临床诊断提供可靠依据 ,从而使本病能够得到早期确诊。 Objective To study the characteristics and the diagnostic value of CT and MRI imaging in spongiform leukoencephalopathy after inhaling heroin vapor. Methods Two patients with spongiform leukoencephalopathy after inhaling heroin vapor were observed in aspects of CT and MRI imaging, and the clinical manifestations and pathological changes were summarized and discussed as well. Results The main symptoms of the two patients were cerebellar ataxia and bradyphrenia. CT showed a symmetrical hypodensity of the white matter in both cerebellar hemispheres and both posterior limbs of the internal capsule. MRI revealed symmetrical hyperintense lesions of demyelination in cerebellar dentatum, the white matter of centrum semiovale, internal capsule, midbrain, and pons. With the literature references, it was suggested that the characteristics of CT and MR imaging in this disease were particular for confirming the diagnosis. Conclusion Spongiform leukoencephalopathy after inhaling heroin vapor has its own characteristics of CT and MR imaging. CT and MR imaging are reliable for confirming the early diagnosis.
出处 《中华放射学杂志》 CAS CSCD 北大核心 2002年第3期210-222,共13页 Chinese Journal of Radiology
关键词 二醋吗啡 脑疾病 体层摄影术 X线计算机 磁共振成像 诊断 海洛因中毒 白质脑病 Diacetylmorphine Brain disease Tomography, X ray computed Magnetic resonance imaging
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  • 1野向春,中风与神经疾病杂志,1999年,5卷,281页

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