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局限性粘液性水肿 被引量：2

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摘要 局限性粘液性水肿是自身免疫性甲状腺疾病的甲状腺外症状之一,多见于Graves病患者,其发病机理尚不完全清楚。目前认为患者皮肤的成纤维细胞上具有促甲状腺素受体样免疫活性蛋白,自身抗体作用促使其合成氨基葡聚糖增多,并局部沉积而引起突眼和局部粘液性水肿。该病多发生于双侧胫骨前,病情与甲状腺激素水平无关。皮质激素局部用药可使轻、中度病变缓解,病情严重者治疗困难。
作者 欧晓红
机构地区 四川大学华西医院核医学科
出处 《国外医学（内分泌学分册）》 2002年第2期95-98,共4页 Foreign Medical Sciences(Section of Endocrinology)
关键词 局限性粘液性水肿 GRAVES病 自身免疫 促甲状腺素 临床特征 治疗 发病机制
分类号 R581.2 [医药卫生—内分泌]
  • 相关文献

参考文献17

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  • 2Cho S, Choi J H, Sung K J, et al. Graves' disease presenting as elephantiasic pretibial myxedema and nodules of the hands[J]. Int J Dermatol,2001,40:276-277.
  • 3Stadlmayr W, Spitzweg C, Bichlmair A M, et al.TSH receptor transcripts and TSH receptor like immunoreactivity in orbital and pretibial fibroblasts of patients with Graves'ophthalmopathy and pretibial myxedema[J]. Thyroid, 1997,7:3-12.
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同被引文献8

  • 1奥多姆.徐世正主译.安德鲁斯皮肤病学[M].北京:科学出版社,2004.613-614.
  • 2Cho S,Chci JH,Sung KJ,et al.Graves' disease presenting as elephaniasic pretibial mixedema and nodules of the hands[J].Int J Dermatol,2001,40(4):276 -277.
  • 3Schwartz KM,Fatourechi V,Ahmed DD,et al.Dermopathy of Graves' disease(pretibial myxedema):long-term outcome[J].J Clin Endocrinol Medtab,2002,87 (2):438 -446.
  • 4纳猛,李兰英,马孝葵,纳锦芳,杨云东,宋杰,李霞.胫前黏液水肿[J].临床皮肤科杂志,2008,37(6):343-344. 被引量：1
  • 5梁碧华,王侠生,朱慧兰.胫前黏液性水肿1例[J].临床皮肤科杂志,2008,37(9):611-611. 被引量：1
  • 6于学勇,戴建华,马惠.粘液性水肿的病理生理机制[J].医学综述,1999,5(9):411-411. 被引量：2
  • 7吴金义,薛晓峰,周艳玲,汲清湘,刘景春,张蕾.黏液性水肿[J].中国社区医师,2002,18(12):13-15. 被引量：2
  • 8李丽,王宝玺,刘跃华,方凯.胫前粘液性水肿[J].临床皮肤科杂志,2002,31(11):676-676. 被引量：4

引证文献2

二级引证文献3

国外医学（内分泌学分册）
2002年 第2期

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