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单核细胞趋化蛋白-1和NF-κB与肾脏疾病 被引量:5

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摘要 趋化因子是一组对白细胞有趋化功能的细胞因子 ,按其结构分为中性粒细胞 (C X C)和单核细胞 (C C)两个亚族 ,单核细胞趋化蛋白 1(MCP 1)属于后一类。肾脏病变时 ,肾组织内白细胞的浸润与MCP 1的表达呈正相关。核转录因子 κB(NF κB)是细胞内一个具有多向性调节作用的核转录因子 ,在细胞因子诱导的基因表达中起关键性的调控作用 ,与肾小球肾炎、肾毒性损害和肾脏疾病进展有关。
作者 肖建武
出处 《国外医学(生理病理科学与临床分册)》 2002年第1期100-102,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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  • 1Morrissey J. Angiotensin and gene expression in the Kidney[J]. Am J kidney Dis, 1998,31:171-179.
  • 2Duque M, Go' mez-Guerrero C, Egido J. Interaction of IgA with Fca Receptors of Human Mesangial Cells Activates Transcription Factor Nuclear Factor-κB and Induces Expression and Synthesis of Monocyte Chemoattractant Protein-1, IL-8, and IFN-Inducible protein[J]. J Immunol, 2000,159:3474 - 3482.
  • 3Banas B, Luckow B, Moller M, et al. Chemokine and chemokine receptor expression in novel human mesangial cell line[J]. J Am Soc Nephrol, 1999,10(11) :2314 - 2322.
  • 4Schlondorff D, Nelson PJ. Chemokines and renal disease[J]. Kidney International, 1997,51: 610 - 621.
  • 5Gesualdo L, Grandaliano G. Monocyte recruitment in cryoglobulinemic membrano proliferative glomerulonephritis: A pathogenetic role for monocyte chemotactic peptide-1 [J]. Kidney Intemational, 1997,51:155 -163.
  • 6Oppenheim JJ, MurPhy WJ, Chertox O. prospects for cytokine and chemokine biotherapy[J]. Clin Cancer Res, 1997,3(12 pt2):2682-2686.
  • 7Schwarz M, Radeke HH, Resch K, et al. Lymphocyte-derived cytokines induce sequential expression of monocyte-and T cell-specific chemokines in human mesangial cells[J]. Kidney Int,2000,52(6): 1521 - 1531.
  • 8Tang WW, Meiying Qi, Warren JS, et al. Chemokine Expression in Experimental Tubulointerstitial Nephritis[J].J Immunol, 1997,159:870-876.
  • 9Donato JA, Hayaawa M, Roth DM, et al. A cytoineresponsive IκB inase that activates the transcription factor NF-κB[J]. Nature,2000,388:548-563.
  • 10Wenzel UA, Schneider A, Abbond HE, et al. Monocyte chemoattractant protein-1 mediates monocyte/macrophage influx in anti-thymocyte antibody-induced glomerulonephritis[J]. Kidney International, 1997,51:770-776.

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