摘要
血小板衍化生成因子 (PDGF)是一种由多种细胞合成和分泌的多功能蛋白质 ,对胶质细胞和间质细胞具有促有丝分裂和趋化作用 ,PDGF及其受体 (PDGFR)在神经系统中广泛表达 ,与缺血性脑血管病的发生密切相关。文章综述了PDGF及其PDGFR的结构、分布、生物学活性 。
PDGF is a multifunctional protein which is synthesized and secreted by several cells.It can make glial and stroma mitosis and chemotaxis.PDGF and its receptor(PDGFR) are generally expressed in nervous system and closely associated with the genesis of ICBVD.The structure,distribution and biological characteristics of the PDGF and PDGFR,mechanism and relation with ICBVD were reviewed in this paper.
出处
《黑龙江医学》
2002年第3期163-164,共2页
Heilongjiang Medical Journal
