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类风湿关节炎双腕RAMRIS评分的临床应用 被引量:1

The correlation between rheumatoid arthritis magnetic resonance imaging score (RAMRIS) of bilateral wrists and disease activity in rheumatoid arthritis
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摘要 目的探讨双腕RAMRIS评分能否替代双手(腕+掌指关节) RAMRIS评分评估类风湿关节炎(rheumatoid arthritis,RA)。方法纳入100例行双手MRI平扫+增强检查的RA患者,男22例,女78例,年龄20~78岁,中位年龄为50岁,均处于疾病活动期。由放射科医生在不知患者病情的情况下根据RAMRIS标准图像分别评估滑膜炎、骨炎及骨侵蚀,计算双腕及双手RAMRIS评分。结果双腕RAMRIS评分部位滑膜炎、骨炎和骨侵蚀的检出率均显著高于掌指关节(P <0. 05)。以双腕MRI代替双手MRI,仅2%的早期RA患者被漏诊滑膜炎,2%的长病程RA患者被漏诊骨侵蚀,1%的早期RA患者和5%的长病程RA患者被漏诊骨炎。双手RAMRIS滑膜炎、骨炎、骨侵蚀评分中,双腕分别占53%、89%、93%。双腕RAMRIS滑膜炎、骨炎及骨侵蚀与HAQ(r=0. 346、0. 303、0. 369,P <0. 01)、CRP(r=0. 356、0. 251、0. 271,P <0. 05)及PAS(r=0. 488、0. 594、0. 639,P <0. 001)呈显著正相关。结论双手MRI病变均多见于腕关节,双腕RAMRIS评分在双手中占比重高,以双腕MRI代替双手MRI对早期或长病程RA患者的滑膜炎、骨炎、骨侵蚀的检出率影响小,双腕RAMRIS滑膜炎及骨侵蚀与HAQ呈正相关,有望替代及简化现有的双手RAMRIS评分。
出处 《广东医学》 CAS 2018年第21期3232-3236,共5页 Guangdong Medical Journal
基金 广东省自然科学基金资助项目(编号:2017A030313777)
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