摘要
目的:探讨乳腺浸润性导管癌(IDBC)自动乳腺全容积成像(ABVS)冠状面的汇聚征与肿瘤临床病理变量的关系。方法:收集160例经病理证实的IDBC患者(160个肿块)的超声影像和临床病理资料,分析ABVS冠状切面的汇聚征的出现与患者临床病理变量的关系。结果:160例中,有汇聚征56例(35.0%),无汇聚征104例(65.0%)。汇聚征在不同年龄、不同肿块大小、不同绝经状态组中出现比例无统计学差异(均P>0.05)。汇聚征在组织学I～II级组和腋窝淋巴结转移组以及在雌激素受体阳性、孕激素受体阳性、表皮生长因子受体阴性、Ki-67阴性组中出现的比例明显增高(均P<0.05)。汇聚征在不同人表皮生长因子受体状态组中出现的比例无统计学差异(P>0.05)。结论:IDBC肿块在ABVS冠状面的汇聚征一定程度上可反映肿瘤临床病理特征,可为临床选择乳腺癌个性化诊断治疗及评估患者预后提供影像学依据。
Objective:To investigate the relationship between the convergence sign in automated breast volume scanner (ABVS)and tumor-associated clinicopathologic variables in patients with invasive ductal breast carcinoma (IDBC). Methods:The ultrasonographic images and clinicopathological data of160IDBC patients(160masses) confirmed by postoperative pathology were collected.The relations of the convergence sign present in the coronal plane of ABVS with the clinicopathologic variables of the patients were analyzed. Results:Of the160patients,convergence sign was seen in56cases(35.0%)and absent in104cases(65.0%). There were no significant differences in proportions of presence of the convergence sign between groups concerning age,tumor size and menopausal status(all P>0.05).The proportions of presence of the convergence sign were increased in groups for histological Ⅰ-Ⅱ grade and axillary lymph node metastases as well as positive estrogen receptor,positive progesterone receptor,negative epidermal growth factor receptor and negative Ki-67 (all P<0.05).The proportions of presence of the convergence sign showed no statistical difference between groups concerning different statuses of human epidermal growth factor receptor2(P>0.05). Conclusion:The convergence sign of the IDBC mass in the coronal plane of ABVS can,to some extent,indicate the clinicopathologic features of the tumor,which may provide imaging evidence for the selection of personalized diagnosis and treatment as well as prognosis estimation for breast cancer in clinical practice.
作者
文欢
肖际东
周元全
贺芳
毛玉瑶
WEN Huan;XIAO Jidong;ZHOU Yuanquan;HE Fang;MAO Yuyao(Department of ultrasound,the Third Xiangya Hospital,Central South University,Changsha410013,China)
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2018年第11期1424-1431,共8页
China Journal of General Surgery
基金
中南大学研究生自主探索创新项目(2017zzts893)
中南大学中央高校基本科研业务费专项资金资助项目
关键词
乳腺肿瘤
癌
导管
乳腺
诊断显像
Breast Neoplasms
Carcinoma,Ductal,Breast
Diagnostic Imaging
clinicopathology,biomarkers
