摘要
抑郁症患者普遍存在着昼夜节律紊乱的症状。文章基于阴阳消长平衡规律,探讨了抑郁症昼夜节律紊乱的中医病因病机。笔者认为抑郁症患者症状出现"晨重"现象与其体内阳气不足以及清晨阳气升发障碍有关;而抑郁症患者常见的夜间入睡困难则主要与阳过盛不能入阴,或阴不足无法制阳,阴阳无法相交有关。有鉴于此,笔者提出对抑郁症患者采用昼夜分时治疗的策略,即清晨(卯时)给予温升阳气的方药,傍晚(酉时)给予滋阴敛阳安神的方药,通过恢复阴阳盛衰消长平衡,从而调整抑郁症患者存在的昼夜节律紊乱,达到缓解或减轻临床症状的效果。期望这一策略的提出能为抑郁症的中医治疗提供新的思路及治疗方向。
Symptoms of circadian rhythm disorder are common in depression patients.The paper discusses TCM pathogenesis and cause of disease of circadian rhythm disorder in depression based on the rule of waxing and waning of yin-yang. It is believed that the phenomenon of ‘aggravated symptoms in the morning'is related to the deficient yang-qi and its recuperating obstacle in the morning.While the symptom of sleeping difficulty in the evening may be caused by the excessive yang-qi can't be into yin,the deficient yin-qi can't astringe yang or disharmony between yin and yang.For this reason,we put forward a timeshared-treatment strategy for patients with depression,as using prescription of warming and recuperating yang-qi during ‘Maoshi'(5:00-7:00)and prescription of nourishing yin-qi to astringe yang-qi for tranquilization during ‘Youshi'(17:00-19:00). The timeshared-treatment strategy may adjust the circadian rhythm disorder in patients with depression to achieve the effect of relieving or alleviating clinical symptoms by restoring balance of waxing and waning of yin-yang.It is expected that the proposed strategy can provide new ideas and treatment directions for treatment of depression by TCM.
作者
陈紫莹
吴丽丽
严灿
CHEN Zi-ying;WU Li-li;YAN Can(Basic Medical School,Guangzhou University of Chinese Medicine,Guangzhou 510006,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2018年第12期5545-5547,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金项目(No.30873389)
国家级大学生创新创业训练计划项目(No.201710572010)~~
关键词
阴阳消长
抑郁症
昼夜节律
分时治疗
Waxing and waning of yin-yang
Depression
Circadian rhythm
Ti