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右美托咪定用于全身麻醉临床观察 被引量:1

Clinical Observation of Dexmedetomidine in General Anesthesia
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摘要 目的探究将右美托咪定应用于全身麻醉中的实际临床效果,并对其安全性进行分析。方法将2016年6月至2018年8月本院麻醉科接收的行全身麻醉的患者86例纳入本研究,谨遵随机分组原则分成观察组(43例)、对照组(43例)。观察组行右美托咪定全麻,对照组行丙泊酚全麻,观察比较组间麻醉效果。结果麻醉后0.5h,观察组患者的收缩压、舒张压均明显高于对照组(P<0.05),其心率明显低于对照组(P<0.05);观察组的窦性停搏、寒颤、心动过缓的发生情况明显少于对照组(P<0.05)。结论在施行全身麻醉过程中应用右美托咪定,对患者的体征指标均起着较好的稳定效果,且不良反应少,麻醉安全性高,可加强推广。 Objective To investigate the actual clinical effect of dexmedetomidine in general anesthesia and toanalyze its safety. Methods Eighty-six patients who received general anesthesia by the Department of Anesthesiologyfrom June 2016 to August 2018 were included in the study. They were divided into observation group (43 cases)and control group (43 cases) according to the principle of randomization. The observation group underwent generalanesthesia with dexmedetomidine, and the control group received general anesthesia with propofol. The anestheticeffect between the groups was observed and compared. Results 0.5 hours after anesthesia, the systolic blood pressureand diastolic blood pressure of the observation group were significantly higher than the control group (P<0.05), andthe heart rate was significantly lower than the control group (P<0.05). The incidence of sinus arrest, shivering andbradycardia in the observation group was significantly less than that in the control group (P<0.05). Conclusion Theapplication of dexmedetomidine in the course of general anesthesia has a good stabilizing effect on the patient's vitalsigns, and the adverse reactions are few. The safety of anesthesia is high and can be promoted.
作者 姜凤琴 JIANG Feng-qin(The Seventh People's Hospital of Zibo,Zibo,Shandong 255040)
出处 《智慧健康》 2018年第32期146-148,共3页 Smart Healthcare
关键词 右美托咪定 丙泊酚 全身麻醉 不良反应 Dexmedetomidine Propofol General anesthesia Adverse reactions
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