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指纹图谱考察常用中药饮片批次稳定性的研究 被引量:4

Batch Stability Study of Commonly Used Herbs in Our Hospital Based on Fingerprint Chromatography
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摘要 目的:从药用部位角度选取代表性常用中药饮片进行研究,考察上海中医药大学附属龙华医院中药饮片的批次稳定性。方法:采用Microsoft Office Excel分析医院中药饮片使用情况;采用指纹图谱技术对选取的中药饮片进行分析。结果:2012年与2013年用量排名前几位的中药饮片基本相同;选取了12种中药饮片,共107批次,进行指纹图谱研究,结果表明,不同批次、产地药材的指纹图谱、已知成分含量、聚类分析树状图差异较大。结论:中药饮片的质量与储存时间、产地以及药材本身的特点等因素均有关,其稳定性确定需综合考虑各因素;指纹图谱技术能够较客观、综合评价中药饮片的质量。 Objective:Traditional Chinese medicine from different parts of plant were selected and researched for investigating batch stability of herbs.Methods:Used situation of herbs was analyzed by Microsoft Office Excel;the selected medicines were studied by HPLC fingerprint chromatography technology.Results:The top use dosage of herbs basically was the same in 2012and 2013;Twelve herbs contained 107batches,was chosen to be researched,and the resuh showed that fingerprint spectrum,component content,cluster analysis tree diagram had a lot of differences.Conclusion:Quality of traditional Chinese medicine is related with storage time,origins,ingredient content and so on;stability determination should consider various factors;Fingerprint chromatography technology can objectively and comprehensively evaluate the quality of herbs.
作者 谢瑞芳 林评兰 赵秋华 石志娜 徐佳琪 周向明 周昕 XIE Rui-fang;LIN Ping-lan;ZHAO Qiu-hua;Sill Zhi-na;XU Jia-qi;ZHOU Xiang-ming;ZHOU Xin(Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China)
出处 《中医药导报》 2018年第20期45-49,55,共6页 Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金 龙医学者(育苗计划)项目(LYTD-49) 上海市临床药学重点专科建设项目
关键词 中药饮片 批次 稳定性 指纹图谱 Traditional Chinese medicine batch stability fingerprint chromatography
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