摘要
目的:观察血府逐瘀汤加味治疗轻中度颅脑损伤患者神经功能缺损程度及血清学指标。方法:随机选取2014年12月~2016年11月在本院治疗的轻中度颅脑损伤患者70例,采用数字表法随机分为实验组和对照组各35例。两组患者均给予常规西医治疗,实验组患者在常规治疗基础上口服血府逐瘀汤加味而成的中药汤剂。根据两组患者治疗前后的神经功能缺损程度、昏迷程度、预后情况、焦虑抑郁情况、自理能力、运动、认知功能、血清指标进行对比分析。结果:本次研究发现两组患者治疗后、组内治疗前后神经缺损功能、昏迷程度、焦虑抑郁情况、自理能力、运动、认知功能以及治疗后的预后情况对比差异显著有统计学意义(P<0. 05);两组患者组内治疗第1、3、7、28天与治疗前血清指标、实验组治疗第3、7、28天的IL-1β水平、第1、3、7天的IL-6水平同对照组对比差异显著有统计学意义(P<0. 05)。结论:血府逐瘀汤加味治疗轻中度颅脑损伤患者能够有效恢复患者神经受损功能、显著降低血清炎症因子水平、改善患者预后情况、自理能力、综合功能,有利于提高轻中度颅脑损伤患者的临床疗效与生活质量。
Objective:To study the degree of neurological deficits and serological indexes in patients with mild to moderate craniocerebral injury treated with Xuefu Zhuyu Decoction.Methods :70 cases were randomly selected from December 2014 to November 2016,and were randomly divided into experimental group and controlled group.The two groups of patients were given conventional western medicine treatment,the experimental group of patients on the basis of conventional treatment of oral administration of Xuefu Zhuyu Decoction.According to the degree of neurological deficits,coma,prognosis,anxiety and depression, self-care ability,exercise,cognitive function and serum index of the two groups before and after treatment.Results :This study found that the two groups of patients after treatment,the group before and after treatment of nerve defect function,coma,anxiety and depression,self-Fare ability,exercise,cognitive function and the prognosis of treatment after the difference was significant, statistically significant (P <0.05).The levels of IL-1β on the 3rd,7th and 28th day of the treatment group were treated on the 1st,3rd,7th and 28th day before treatment.The levels of IL-6 were significantly different from those of the controlled group (P <0.05).Conclusion:Xuefu Zhuyu Decoction can be used to treat patients with mild to moderate craniocerebral injury,which can effectively restore the nerve impaired function,reduce the level of serum inflammatory factors,and improve the prognosis of patients,self-care ability,comprehensive function,clinical efficacy and quality of life in patients with brain injury.
作者
李东
LI Dong(Department of Neurosurgery,Shandong Hospital of Traditional Chinese Medicine ,Shouguang Shandong 262700,China)
出处
《四川中医》
2018年第11期137-140,共4页
Journal of Sichuan of Traditional Chinese Medicine
基金
2018年潍坊市卫生计生委中医药科研项目(编号:wfwsjs-003-005)
关键词
血府逐瘀汤
神经功能缺损程度
血清学指标
Xuefu Zhuyu Decoction
Neurological deficits
Serological indicators
