摘要
目的总结1例重型再生障碍性贫血-Ⅱ型患者的移植护理经验,探讨二次骨髓移植治疗疑难重症血液病的护理方法。方法采取严密感染防控措施,强化预处理用药观察及消化道黏膜炎、出血性膀胱炎、癫痫等并发症的护理,选用外周静脉留置针作为静脉通路进行合理导管管理及给予有效心理护理。结果患者顺利渡过长达52d的严重粒缺期(中性粒细胞绝对值<0.1×109/L),并发症得到有效控制,造血干细胞顺利植入并出仓。结论经过上述护理干预措施能够有效降低感染及并发症的风险,为二次骨髓移植的成功提供保障。
Objective To summarize the nursing care for one successful haploidentical allogeneic bone marrow transplantation (haplo-BMT)for one patient with severe aplastic anemia type-Ⅱ(SAA-Ⅱ).The patient accepted an umbilical cord blood transfusion sequentially combined with the second haplo-BMT after an engraftment failure of the first haplo-BMT.The experience of nursing care will be discussed and shared for patients with a second haplo-BMT.Methods The comprehensive nursing cares were utilized during haplo-BMT,it included preventive measures for secondary infections,closely control of side effects, promptly nursing intervention for gastrointestinal mucositis,hemorrhagic cystitis and epilepsy,psychological nursing for appeasing emotional variations,and addition of intravenous indwelling needle if necessary.Results The patient achieved a successful stem cell engraftment and survived a long-term granulopenia (granulocytes <0.1x 109/L)which lasted for 52days with a recovery of varied complications. Conclusion The comprehensive nursing care can reduce the risk for secondary infections and other complications,it shed a new light on second allogeneic bone marrow transplantation for complicated patients.
作者
庄雪莲
吕红霞
周栋
谢佳君
杨岩
张静静
Zhuang Xuelian;Lyv Hongxia;Zhou Dong;Xie Jiajun;Yang Yan;Zhang Jinxing(Department of Hematology,Dalian Key Laboratory of Hematology,and Liaoning Medical Center for Hematopoietic Stem Cell Transplantation,of the Second Hospital of Dalian Medical University,Dalian 116027,China)
出处
《中国实用护理杂志》
2018年第35期2770-2774,共5页
Chinese Journal of Practical Nursing
基金
大连市医学科学研究计划(1712040).
关键词
重型再生障碍性贫血Ⅱ型
异基因骨髓移植
二次骨髓移植
移植护理
Severe aplastic anemia type II
Allogeneic bone marrow transplantation
Second bone marrow transplantation
Nursing care for bone marrow transplantation