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超声检查预测困难气道的价值:meta分析

Value of ultrasonography in predicting difficult airway: a meta-analysis
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摘要 目的 采用meta分析评价超声检查预测困难气道的价值.方法 计算机检索数据库PubMed、Embase、Cochrane Library和CNKI数据库,纳入超声检查预测困难气道的文献,结局指标为困难气道预测的真阳性数(TP)、假阳性数(FP)、真阴性数(TN)和假阴性数(FN).采用Meta-DiSc1.4软件行异质性分析及合并效应量.根据提取的TP、FP、TN、FN,计算各纳入文献的评价指标,包括灵敏度(Sen)、特异度(Spe)、阳性似然比(PLR)、阴性似然比(NLR)、诊断比值比(DOR)及其95%可信区间(95%CI).通过Sen和Spe生成综合受试者工作特征曲线,计算曲线下面积(AUC).以合并效应量后Sen、Spe、PLR、NLR、DOR及其95%CI和AUC及其95%CI评估超声检查预测困难气道的价值.结果 本研究共纳入9篇文献,包括3 525例患者,合并效应量后,Sen、Spe、PLR、NLR、DOR及其95%CI分别为0.69(95%CI 0.63 ~ 0.74)、0.84(95%CI 0.82~0.85)、5.79(95%CI 3.67~9.14)、0.36(95%CI 0.27~0.46)、22.04(95%CI 10.68~ 45.45),AUC为0.89(95%CI 0.84~0.94).结论 超声检查可准确预测困难气道. Objective To systematically review the value of uhrasonography in predicting difficult airway.Methods Databases including PubMed,Embase,Coehrane Library and CNKI were searched for trials involving the value of ultrasonography in predicting difficult airway.Outcome parameters were true positive,false positive,true negative and false negative.The pooled estimates and heterogeneity among the included studies were performed with Meta-DiSc 1.4software.The evaluation indexes including sensitivity, specificity,positive likelihood ratio,negative likelihood ratio,diagnostic odds ratio and the 95%confidence interval (CI)were calculated according to true positive,false positive,true negative and false negative extracted from selected studies.The receiver operating characteristic curves were plotted according to sensitivity and specificity,and the area under the curve was calculated.The overall pooled sensitivity,specificity,positive likelihood ratio,negative likelihood ratio,diagnostic odds ratio,95%CI and area under the curve were used to assess the value of ultrasonography in predicting difficult airway.Results Nine trials involving 3525patients were included in this meta-analysis.The overall pooled sensitivity,specificity, positive likelihood ratio,negative likelihood ratio and diagnostic odds ratio of the included studies were 0.69(95%CI 0.63-0.74),0.84(95%CI 0.82-0.85),5.79(95%CI 3.67-9.14),0.36(95%CI 0.27-0.46),22.04(95%CI 10.68-45.45),respectively.The area under the curve was 0.89(95% CI 0.84-0.94).Conclusion Ultrasonography can accurately predict difficult airway.
作者 计超 倪强 陈武荣 Ji Chao;Ni Qiang;Chen Wurong(Department of Anesthesiology,Putuo Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200062,China)
出处 《中华麻醉学杂志》 CAS CSCD 北大核心 2018年第6期715-718,共4页 Chinese Journal of Anesthesiology
关键词 超声检查 插管法 气管内 预测 Ultrasonography Intubation,intratracheal Forecasting
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