摘要
目的 评价超声清创对糖尿病足溃疡(DFU )的疗效. 方法 系统检索数据库和杂志中关于超声清创治疗DFU的随机对照试验、类实验性研究及队列研究,双人对文献进行筛检、质量评价和资料提取,对符合质量标准的研究进行M eta分析. 结果 共纳入6项研究,总共624例患者.与传统清创比较,超声清创伤口平均愈合时间短,M eta分析显示差异有统计学意义[合并效应量(WMD)= -20.78 ,95% CI :-35.72~ -5.85 ,P=0.006] ;共3项研究结局指标含有患者伤口平均愈合率,Meta分析显示差异有统计学意义(WMD=22.53 ,95% CI :19.19~25.87 ,P<0.001) ;共2项研究结局指标含有患者伤口平均愈合面积,但Meta分析显示差异无统计学意义(WMD= -5.82 , 95% CI :-18.43~6.80 ,P=0.370). 结论 超声清创治疗DFU优于传统清创.
Objective To evaluate the effect of ultrasonic debridement for treating diabetic foot ulcers (DFU). Methods Randomized controlled trials ,quasi-experimental studies and cohort studies of ultrasonic debridement for DFU were searched from the Cochrane Library ,PubMed ,EMbase ,CBM ,VIP and CNKI. Two authors screened ,evaluated and extracted research articles ,and conducted meta-analysis on studies that met the quality standards. Results A total of six studies including 624 patients were included. Of them ,four studies included the outcome on the average wound healing time ,and meta-analysis showed that ,compared with traditional debridement ,ultrasonic debridement could shorten the average healing time for wounds[weighted mean differences(WMD)= -20.78 ,95% CI :-35.72-5.85 ,P=0.006].Three studies included the outcome on the average wound healing rate ,and meta-analysis showed that ultrasonic debridement had a higher average wound healing rate than traditional debridement (WMD=22.53 ,95% CI :19.19~25.87 ,P<0.001). Two studies included the outcome on the average wound healing area ,and meta-analysis showed no significant difference between ultrasonic debridement and traditional debridement (WMD= -5.82 ,95% CI :-18.43~ 6.80 ,P= 0.370). Conclusions Ultrasonic debridement is superior to traditional debridement in treating diabetic foot ulcers.
作者
徐亚青
安艳军
郑宋宋
姬琳
Xu Yaqing;An Yanjun;Zheng Songsong;Ji Lin(Department of Endocrinology,Zhejiang Chinese Medical University Affiliated Hospital of Integrated Traditional Chinese and Western Medicine,Hangzhou Red Cross Hospital,Hangzhou 310000,China)
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2018年第12期1412-1415,共4页
Chinese Journal of Geriatrics
基金
杭州市卫生科技计划项目(2017A39)。
