摘要
目的:分析眼眶肿瘤摘除手术并发症的发生情况,并探讨术后预后的影响因素,以期为眼眶肿瘤的临床治疗提供相关参考。方法:对2008年1月至2017年12月就诊于三峡大学附属仁和医院眼科的101例眼眶肿瘤摘除手术患者临床及治疗资料进行回顾性分析,统计术后出现的各种并发症,按照随访结果,将术后患者分为预后不良组和预后良好组,采用单因素及多因素Logistic回归模型分析患者术后预后不良的相关危险因素。结果:在本组101例手术患者中,术后发生并发症的患者32例(38例次),术后并发症发生率为31. 68%,主要并发症有眼球运动障碍、视力障碍、上睑下垂、球后出血、散瞳等。多因素Logistic回归分析结果显示:眶内肿瘤(OR=6. 366)、恶性肿瘤(OR=5. 972)、肿瘤累及至深部(OR=7. 149)、肿瘤边界不清晰(OR=6. 215)、存在合并症(OR=5. 124)、肿瘤分化程度为低分化(OR=4. 221)是眼眶肿瘤摘除术预后不良的独立危险因素(P <0. 05)。结论:眶内肿瘤、眶内恶性肿瘤、肿瘤累及至深部、肿瘤边界不清晰、存在合并症、肿瘤低分化程度为低分化是眼眶肿瘤摘除术预后不良的独立危险因素。
Objective: To analyze the occurrence of complications after orbital tumor resection and to explore the impact factors of prognosis,so as to provide relevant references for the clinical treatment of orbital tumors. Methods: A retrospective analysis was conducted for 101 patients with orbital tumors treated in the Department of Ophthalmology of Affiliated Renhe Hospital of China Three Gorges University from January 2008 to December 2017. The postoperative complications were counted. Patients were divided into the poor prognosis group and the good prognosis group according to follow-up results. Univariate and multivariate logistic regression model were used to analyze the risk factors of poor prognosis. Results: Among101 cases,32 cases( 38 times) had postoperative complications. The incidence of postoperative complications was 31. 68%.The main complications include dyskinesia,visual impairment,ptosis,retrobulbar hemorrhage and mydriasis. Multivariate logistic regression analysis showed that intraorbital tumors( OR = 6. 366),malignant tumors( OR = 5. 972),deep involvement( OR = 7. 149),unclear tumor margin( OR = 6. 215),presence of complications( OR = 5. 124),and low differentiation( OR = 4. 221) were independent risk factors of poor prognosis after orbital tumor resection( P < 0. 05). Conclusion:Orbital tumors,intraorbital malignancies,deep involvement of the tumor,unclear tumor boundaries,presence of complications,and low differentiation of the tumor are independent risk factors of poor prognosis of orbital tumor resection.
作者
韩玉灿
王平
谭容
龚晋
杨庆国
Han Yucan;Wang Ping;Tan Rong;Gong Jin;Yang Qingguo(Department of Ophthalmology,Affiliated Renhe Hospital of China Three Gorges University,Second Clinical Medical College of China Three Gorges University,Yichang 443001,Hubei,China)
出处
《肿瘤预防与治疗》
2018年第6期406-410,共5页
Journal of Cancer Control And Treatment
关键词
眼科肿瘤
手术
并发症
危险因素
Ophthalmic neoplasms
Surgery
Complications
Risk factors
