摘要
轻度卒中往往因为症状轻微、风险获益比不明确而被排除在静脉溶栓(intravenous thrombolysis,IVT)治疗之外.但近年来,越来越多的研究证实约1/3未接受IVT治疗的轻度卒中患者转归不良.虽然大量研究显示IVT治疗可降低轻度卒中患者的致残率和致死率,但也有相关研究认为并无获益,有关轻度卒中患者是否需要IVT治疗成为目前的研究热点.文章就轻度卒中的转归、IVT治疗是否获益以及哪些轻度卒中患者适合IVT治疗等相关问题进行了综述.
Mild strokes are often excluded from intravenous thrombolysis (IVT) because of their mild symptoms and unclear risk-benefit ratio. However, in recent years, more and more studies have confirmed that about 1/3 of patients with mild stroke who have not received IVT have a poor outcome. Although a large number of studies have shown that IVT treatment can reduce the morbidity and mortality of patients with mild stroke, relevant studies also consider that they do not benefit from it. Whether need to be treated with IVT in patients with mild stroke has become a hot research topic. This article reviews the outcomes of mild stroke, whether IVT treatment is beneficial, and which patients with mild stroke are eligible for IVT treatment.
作者
冯海霞
吴军
Feng Haixia;Wu Jun(Department of Neurology,Peking University Shenzhen Hospital,Shenzhen 518036,China;Shantou University Medical College,Shantou 515041,China)
出处
《国际脑血管病杂志》
2018年第10期761-766,共6页
International Journal of Cerebrovascular Diseases
