摘要
目的探讨七氟烷联合瑞芬太尼在小儿日间手术麻醉中的应用效果。方法 2013年2月至2016年12月选择进行择期唇腭裂修补术患儿66例,随机分为2组,每组33例。对照组给予氯胺酮联合丙泊酚麻醉,观察组给予七氟烷联合瑞芬太尼麻醉,记录2组麻醉效果与苏醒情况。结果所有患儿在麻醉诱导后(T1)、手术开始时(T2)、手术开始后5 min(T3)、手术结束时(T4)的心率和血氧饱和度均表现正常,组内与组间差异都无统计学意义(P> 0. 05)。观察组患儿的自主睁眼时间与拔管时间分别为(7. 62±2. 48) min和(9. 90±4. 22) min,都低于对照组的(12. 89±4. 22) min和(16. 33±7. 28) min(P <0. 05)。观察组患儿围术期躁动、喉水肿、屏气和呛咳等并发症发生率为6. 1%,低于对照组的36. 4%(P <0. 05)。结论七氟烷联合瑞芬太尼应用于小儿日间手术麻醉,能维持患儿生命体征稳定,麻醉诱导迅速,术毕苏醒快,能减少围术期并发症的发生。
AIM To discuss the anesthetic effects of sevoflurane combined remifentanil in pediatric day sur-gery. METHODS From February 2013 to December 2016,66 children in our hospital for elective cleft lip andpalate repair were randomly divided into 2 groups,with 33 children in each group. The control group was givenketamine combined with propofol anesthesia,the observation group was given sevoflurane combined with remifen-tanil anesthesia,and anesthesia and recovery situation of two groups were recorded. RESULTS The heart rateand blood oxygen saturation of all children after induction of anesthesia ( T 1 ) ,at the beginning of operation ( T 2 ) ,5 min after operation ( T 3 ) and at the end of operation ( T 4 ) were within the normal range,and there were no sig-nificant differences between the 2 groups ( P >0. 05) . The time of eye opening and the time of extubation were( 7. 62 ±2. 48) min and ( 9. 90 ±4. 22) min in the observation group,which were lower than ( 12. 89 ±4. 22) minand ( 16. 33 ±7. 28) min in the control group ( P <0. 05) . The perioperative period incidences of complicationssuch as restlessness,laryngeal edema,breath holding and coughing were 6.1% in the observation group,and were36.4% in the control group respectively,and those in the observation group were lower than those in the controlgroup ( P <0.05) . CONCLUSION The application of sevoflurane combined with remifentanil in pediatric day sur-gery can maintain the children stable vital signs,accelerate the induction time of anesthesia and increase the postop-erative recovery quickly,so it has good application values.
作者
阚济伟
KAN Jiwei(Department of Anesthesiology,Tianjin United Family Hospital,Tianjin 300221,China)
出处
《中国临床药学杂志》
CAS
2018年第6期403-405,共3页
Chinese Journal of Clinical Pharmacy
关键词
七氟烷
瑞芬太尼
小儿
日间手术
并发症
sevoflurane
remifentanil
child
day surgery
complication
