摘要
目的分析甲状腺功能亢进症患者药物治疗依从性的影响因素。方法选择2015年1月-2017年12月药物治疗的甲状腺功能亢进症患者88例,比较不同情况患者的依从性,并进行单因素与多因素分析。结果88例患者中依从性好58例(65. 91%),依从性差30例(34. 09%)。单因素检验:不同年龄、性别、文化层次、婚姻状态、月收入、心理反应、家庭支持、甲状腺功能亢进症及药物治疗知识、医疗费用、药物治疗不良反应、医患关系患者的依从性比较差异均有统计学意义(P <0. 05)。Logistic回归分析:甲状腺功能亢进症药物治疗依从性影响因素为甲状腺功能亢进症及药物治疗知识缺少(OR=4. 69,95%CI:1. 26-19. 29)、药物治疗不良反应(OR=4. 18,95%CI:2. 02-21. 28)、存在心理反应不良(OR=3. 30,95%CI:1. 48-18. 20)、患者年龄≥60岁(OR=2. 95,95%CI:1. 31-17. 06)。结论甲状腺功能亢进症患者药物治疗依从性较差,影响因素多种多样,应实施针对性措施提高甲状腺功能亢进症患者药物治疗依从性。
Objective To analyze the influencing factors of drug treatment compliance in patients with hyperthyroidism. Methods 88 cases of patients with hyperthyroidism who were treated with drugs from January 2015 to December 2017 were selected,the treatment compliance of different patients was compared,and single factor and multivariate analysis were performed. Results Among the 88 patients,58 patients (65. 91%) had good compliance,and 30 patients (34. 09%) had poor compliance. Univariate test:the differences in compliance between patients of different age,gender,cultural level,marital status,monthly income,psychological response,family support,hyperthyroidism and drug treatment knowledge,medical expenses, adverse drug reactions,and doctor-patient relationship were statistically significant(P < 0. 05). Logistic regression analysis: lack of knowledge of hyperthyroidism and drug therapy(OR = 4. 69,95% CI:1. 26. 19. 29),adverse drug reactions(OR = 4. 18,95%CI:2. 02 -21. 28),there was a poor psychological reaction(OR =3. 30,95% CI:1. 48 -18. 20),and the patients' age was ≥60 years old(OR =2. 95,95%CI:1. 31 -17. 06) were the influencing factors of medication compliance for hyperthyroidism. Conclusion The compliance of the patients with hyperthyroidism is poor and the influencing factors are varied,the compliance measures should be carried out to improve the compliance of the patients with hyperthyroidism.
作者
郝艳
HAO Yan(Department of Endocrinology,Taihu Hospital of Wuxi,Jiangsu Province,Wuxi 224000,China)
出处
《临床合理用药杂志》
2018年第34期23-25,共3页
Chinese Journal of Clinical Rational Drug Use
