摘要
目的探讨康妇灵胶囊联合抗生素对慢性盆腔炎(CPID)患者的临床治疗效果。方法选取我院妇科门诊及病房2016年3月～2017年4月收治的106例CPID患者,按治疗方式不同分为两组,每组各53例。对照组采用左氧氟沙星+甲硝唑静滴治疗,治疗组在对照组基础上联用康妇灵胶囊治疗。两组均治疗14 d。记录两组临床治疗效果、血清白介素1(IL-1)、白介素2(IL-2)水平及治疗后不良反应发生率。结果治疗组治疗总有效率为94.34%,高于对照组的54.72%,差异有统计学意义(P<0.05)。治疗前,两组IL-1、IL-2水平比较,差异无统计学意义(P>0.05);治疗后,两组IL-1水平均降低,IL-2水平均升高,差异有统计学意义(P<0.05);治疗后治疗组IL-1低于对照组,IL-2高于对照组,差异均有统计学意义(P<0.05);两组治疗后不良反应总发生率比较,差异无统计学意义(P>0.05)。结论对CPID患者在常规抗生素治疗基础上加用康妇灵胶囊可提高临床治疗效果,调节炎症和抗炎的动态平衡,安全可靠。
Objective To investigate the clinical efficacy and effect of Kangfuling Capsules combined with antibiotics on patients with chronic pelvic inflammatory disease (CPID).Methods 106 patients with CPID from March 2016 to April 2017 in our hospital were selected and divided into two groups according to different treatment methods,53 cases in each group.The control group was treated with Levofloxacin +Metronidazole "intravenous infusion.The treatment group was treated with Kangfuling Capsules on the basis,of the control group,and both groups were treated for 14 days. The clinical efficacy,serum interleukin-1(IL-1),IL-2 levels and the incidence of adverse reactions after treatment were recorded.Results The total effective rate was 94.34%in the treatment group and 54.72%in the control group.The difference was statistically significant (P<0.05),before treatment,there was no significant difference in the levels of IL-I,I1-2(P>0.05);the IL-I levels of the two groups was decreased,and the IL-2 level was increased,the differences were statistically significant (P<0.05).After treatment,the IL-1 was lower than that in the control group and the IL-2 was higher than that in the control group,the differences were statistically significant (P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05).Conclusion The addition of Kangful- ing Capsules to patients with CPID on the basis of conventional antibiotic therapy can improve clinical efficacy and regulate the dynamic balance of inflammation and anti-inflammatory,which is safe and reliable.
作者
林晓敏
黄建莲
LIN Xiao-min;HUA NG Jian-lian(Department of Obstetrics and Gynecology,Puning Maternal and Child Health Family Planning Service Center,Guangdong Province,Puning 515300,China)
出处
《中国当代医药》
2018年第35期95-97,共3页
China Modern Medicine
关键词
康妇灵胶囊
慢性盆腔炎
抗生素
白介素-1
白介素-2
Kangfuling Capsules
Chronic pelvic inflammatory disease
Antibiotic
Interleukin-1
Interleukin-2
