摘要
目的分析妊娠期健康妇女血清铁、血清铁蛋白、血红蛋白在妊娠期的水平及变化规律,并探讨铁缺乏与贫血的关系。方法将于郑州大学第三附属医院定期产检的438名妊娠期健康妇女分别于妊娠早、中、晚期采集空腹静脉血一次,测定其血清铁、血清铁蛋白及血红蛋白水平。结果妊娠期健康妇女早、中、晚期血清铁的水平(95%CI)分别为8. 13～8. 88mmol/L、8. 00～8. 26 mmol/L、7. 68～8. 00 mmol/L,妊娠期健康妇女早、中、晚期血清铁蛋白的水平(95%CI)分别为44. 78～65. 16μg/L、24. 14～31. 11μg/L、13. 29～16. 38μg/L,妊娠期健康妇女早、中、晚期血红蛋白的水平(95%CI)分别为124. 48～129. 29 g/L、121. 66～125. 26 g/L、119. 34～124. 26 g/L。妊娠期健康妇女血清铁、血清铁蛋白、血红蛋白水平随着妊娠孕周的增加逐渐降低。438例妊娠期健康妇女在妊娠过程中有121例(27. 6%)发生了铁缺乏,其中贫血者64例(52. 9%);机体铁正常的孕妇318例(72. 4%)中有43例(13. 5%)发生了贫血,两组比较差异有统计学意义。结论分析妊娠期妇女铁水平变化,并研究铁缺乏与贫血的关系,可了解妊娠期妇女机体铁的水平状态,用于指导妊娠期铁的补充,降低贫血及其他铁相关疾病的发生率。
Objective To Analysis the levels and changes of serum iron、serum ferritin and hemoglobin of pregnant women,and explore the relationship between iron deficiency and anemia Methods The fasting venous blood samples were collected from 438 healthy pregnant women during early pregnancy period,middle pregnancy period and late pregnancy period. The levels of serum iron,serum ferritin and hemoglobin were measured. Results The serum iron levels( 95% confidence interval) in different pregnancy periods were 8. 13-8. 88mmol/L,8. 00-8. 26mmol/L and 7. 68-8. 00mmol/L,respectively. The serum ferritin levels( 95% confidence interval) in different pregnancy periods were 44. 78-65. 16ug/L,24. 14-31. 11ug/L and 13. 29-16. 38ug/L,respectively. The hemoglobin levels ( 95% confidence interval) in different pregnancy periods were 124. 48-129. 29g/L,121. 66-125. 26g/L and 119. 34-124, respectively. 26g/L. There were 121 ( 27. 6%) pregnant women with iron deficiency,including 64( 52. 9%) anemic pregnant women. There were 318( 72. 4%) pregnant women without iron deficiency,including 43( 13. 5%) anemic pregnant women. The differences between two groups had statistical significance. Conclusion By analyzing the changes of serum iron,serum ferritin and hemoglobin of pregnant women,we could know the relationship between iron deficiency and anemic,complement iron reasonably during pregnancy, and reduce the occurrence of iron-related diseases.
作者
罗晓华
史娜
郭晓珮
翟闪闪
潘瓷
王晓辉
LUO Xiao Hua;SHI Na;GUO Xiao Pei;ZHAI Shah Shan;PAN Ci;WANG Xiao Hui(Department of Gynaecology and Obstetrics,The Third Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)
出处
《中国妇幼卫生杂志》
2019年第1期35-38,共4页
Chinese Journal of Women and Children Health
基金
郑州市科技厅项目(CZSYJJ15032)
