摘要
内耳疾病是一类以耳鸣、耳聋、眩晕为主要临床表现的疾病。其发病机制不清,过去通常认为与血管问题有关,如血栓、血管狭窄等,然而近期越来越多的研究发现,其可能与变态反应介导的多种因素相关。本文就内耳疾病中梅尼埃病可能的免疫相关发病机制,如I型变态反应、自身免疫、循环免疫复合物、免疫遗传等作一综述。
Inner ear disease is characterized by tinnitus,deafness and vertigo.The pathogenesis remains unknown.In the past,it is considered to be related to vascular disease such as thrombus and hemadostenosis.However,more and more researches indicate that it may be associated with multiple factors mediated by allergy.This paper reviews some possible pathogenesis of Meniere disease,including type I allergy,autoimmunity,circulating immune complex and immune genetic.
作者
郭苏影
张祎
刘博
Guo Suying;Zhang Yi;Liu Bo(Department of Otorhinolaryngology Head and Neck Surgery,Beifing Tongren Hospital,Beijiing 100730,China;Capital Medical University,Beijing Institute of Otorhinolaryngology,Beijiing 100730,China;Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University),Ministry of Education ,Beijiing 100730,China)
出处
《中华耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2018年第12期953-956,共4页
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
基金
“十二五”国家科技支撑计划(2012BA112802).
