摘要
放疗是宫颈癌的重要治疗手段,局部晚期宫颈癌的治疗主要依赖体外放疗和腔内后装放疗。宫颈癌放疗过程中,阴道既是治疗的靶器官,也是重要的危及器官,当其受到较高辐射剂量时,必定会发生放射性损伤。阴道放射性损伤及其所致的性功能障碍成为宫颈癌幸存者长期困扰的重要问题。本文将对近几年有关阴道剂量学和阴道放射性损伤的相关研究进行总结归纳,探究其病理变化、临床表现及诊治预防。
Radiotherapy is an important treatment of cervical cancer,the treatment of locally advanced cervical cancer mainly depends on external beam radiotherapy and brachytherapy.However,in the process of the cervical cancer radiotherapy,the vagina has an ambivalent role in the treatment of cervical cancer,being as well a target organ (upper vagina)as an organ at risk.Vaginal radiation-induced injury will appear when it received high doses of radiation.And sexual dysfunction caused by radiation-induced injury has become an important problem cervical cancer survivor.In this article,recent vaginal dose and vaginal radiation injury-related studies have been summarized to unravel the pathophysiological changes,clinical symptoms,clinical diagnosis and treatment of vaginal radiation-induced injury.
作者
张恺铄
刘孜
汪涛
苏进
施璠
王娟
Zhang Kaishuo;Liu Zi;Wang Tao;Su Jin;Shi Fan;Wang Juan(Department of Radiation Oncology,First affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China)
出处
《中华放射肿瘤学杂志》
CSCD
北大核心
2019年第1期69-73,共5页
Chinese Journal of Radiation Oncology
关键词
放射性损伤
研究进展
宫颈/放射疗法
Radiation-induced injury
Research progress
Cervical neoplasmsyr/radiotherapy
