摘要
目的分析标准四联疗法与序贯疗法在胃溃疡幽门螺杆菌(Hp)阳性患者中的应用效果。方法 71例胃溃疡Hp阳性患者,采用随机数字表法分为试验组(35例,采用序贯疗法治疗)和对照组(36例,采用标准四联疗法治疗)。比较两组患者的临床疗效及Hp清除率。结果试验组患者治疗总有效率为97.14%,显著高于对照组的72.22%,差异有统计学意义(P<0.05)。试验组34例患者Hp清除, Hp清除率为97.14%(34/35);对照组25例患者Hp清除, Hp清除率为69.44%(25/36);试验组Hp清除率显著高于对照组,差异有统计学意义(P<0.05)。结论序贯疗法可有效改善胃溃疡Hp阳性患者病情,提高Hp清除率,促进胃溃疡愈合,效果显著,值得借鉴。
Objective To analyze the effect of standard quadruple therapy and sequential therapy in Helicobacter pylori(Hp) positive patients with gastric ulcer. Methods A total of 71 Hp positive patients with gastric ulcer were divided by random number table into experimental group(35 cases, receiving sequential therapy) and control group(36 cases, receiving standard quadruple therapy). The clinical efficacy and Hp clearance rate between the two groups was compared. Results The experimental group had significantly higher total treatment effective rate as 97.14% than 72.22% in the control group, and the difference was statistically significant(P<0.05). The experimental group had 34 cases with Hp clearance, with Hp clearance rate as 97.14%(34/35), while the control group had 25 cases with Hp clearance, with Hp clearance rate as 69.44%(25/36). The experimental group had significantly higher Hp clearance rate than the control group, and the difference was statistically significant(P<0.05). Conclusion Sequential therapy shows remarkable effect, and it can effectively improve condition of patients with Hp positive gastric ulcer, improve Hp clearance rate, and promote the healing of gastric ulcer. It is worth reference.
作者
梅相群
陈启辉
MEI Xiang-qun;CHEN Qi-hui(Department of Gastroenterology,Lufeng People's Hospital,Lufeng 516500,China)
出处
《中国实用医药》
2019年第2期77-79,共3页
China Practical Medicine
关键词
标准四联疗法
序贯疗法
胃溃疡
幽门螺杆菌
效果
Standard quadruple therapy
Sequential therapy
Gastric ulcer
Helicobacter pylori
Effect
