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抗菌肽生物活性及其作用机理研究进展 被引量:13

Research Progress on Antimicrobial Peptides Bioactivity and its Mechanism
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摘要 抗菌肽(Antibacterial peptides,AMPs)又名抗微生物肽,是一类具有热稳定性好、水溶性好、强碱性和广谱抗菌活性等特点的小分子多肽,具有抵抗外界微生物侵害的作用,并且它是先天免疫物质的重要组成部分。可在饲料生产和畜禽生产中逐渐替代抗生素,是目前国际公认的抗生素替代品。本文综述了抗菌肽的理化性质、来源、生物活性和作用机理。 Antimicrobia peptides (AMPs)are a kind of small molecular peptides and they have many advantages,such as good heat stability,strong antibacyerial activity,broad-spectrum antibacterial and antimicrobial resistance.Antimicrobia peptides have the function of the violation against outside microorganisms.And it is an important component,part of the innate immune system.Antimicrobia peptides are gradually replacing antibiotics in feed production and livestock production.It is internationally acknowledged to be the best an- tibiotic alternative.This article has reviewed the physical and chemical properties,sources,biological activities and mechanism of antimicrobial peptides.
作者 王为栋 孙海娟 Wang Weidong;Sun Haijuan(Weihai Huancui district wenquan animal husbandry and veterinary center station,Weihai,264200,China)
出处 《当代畜牧》 2018年第11期32-34,共3页 Contemporary Animal Husbandry
关键词 抗菌肽 理化性质 生物活性 作用机理 antibacterial peptides physical and chemical properties biological activities mechanism
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