摘要
标题化合物是一种重要的有机中间体。本文以3-(4,4,5,5-四甲基-1,3-二氧硼烷-2-基)苯胺为起始原料经过一锅法合成了目标化合物。该方法的原料廉价易得,操作简便易控,产品纯度较高,适合应用在工业化生产中。产品收率为80.1%。
The title compound is an important pharmaceutical chemical intermediates. In this paper, the target compound was synthesized by one-pot reaction with 3-(4,4,5,5-tetramethyl-1,3-dioborane-2-yl)aniline as the starting material. The structure was confirmed by 1H NMR. The raw materials are cheap and easy to get in this method with high purity. The total yield was 80.1 %.
作者
黄丁
熊昌娟
姜凤鸣
毛燕
黄靖
周志旭
Huang Ding;Xiong Changjuan;Jiang Fengming;Mao Yan;Huang Jing;Zhou Zhixu(School of Pharmaceutical Sciences,Guizhou University,Guiyang 550025;Guizhou Engineering Laboratory for Synthetic Drugs,Guiyang 550025,China)
出处
《广东化工》
CAS
2019年第1期8-8,4,共2页
Guangdong Chemical Industry
基金
贵州大学大学生"SRT计划"项目
合同编号:贵大SRT字(2017)188号
