摘要
目的:观察耳穴压豆联合唑来膦酸治疗去势抵抗性前列腺癌骨转移疼痛的临床疗效。方法:选取53例经确诊去势抵抗性前列腺癌伴骨转移疼痛患者,随机分为对照组25例和观察组28例,观察组采用耳穴压豆联合唑来膦酸治疗,对照组单纯采用唑来膦酸治疗。评价两组患者治疗前后骨痛缓解评分(VAS)和生活质量PROSQOLI评分。结果:两组患者治疗后生活质量指标评分高于治疗前(P <0. 05),而且观察组评分明显优于对照组,差异有统计学意义(P <0. 05);两组患者疼痛评分较治疗前均有下降,差异有统计学意义(P <0. 05);观察组骨痛的缓解程度明显优于对照组,差异有统计学意义(P <0. 05);观察组骨痛缓解所需时间及疗效的维持优于对照组,差异比较具有统计学意义(P <0. 05)。结论:耳穴压豆联合唑来膦酸治疗转移性去势抵抗性前列腺癌患者,可有效缓解骨转移疼痛并提高患者生活质量,值得临床推广。
Objective To observe efficacy of auricular point sticking combined with Zoledronic acid in the treatment of castrate -resistant prostate cancer with bone metastasis.Methods A total of 53 cases of castrate -resistant prostate cancer with bone metastasis were randomly divided into two groups.The patients (28 Cases)in observation group received auricular point sticking combined with Zoledronic acid,while 25 patients in the control group had Zoledronic acid only.Before and after treatment,PROSQOLI scores (quality of life)and pain relief scores (VAS)were observed in the two groups.Results More scores in the quality of life were higher in the two groups after treatment (P <0.05),and more improved quality of life was higher in the observation group than in the control group (P < 0.05).The bone-pain relief rate was higher in the observation group than in the control group (P <0.05),and it spent less time on relieve bone -pain in the observation group than in the control group (P <0.05).Conelusion Auricular point sticking combined with Zoledronic acid ,can achieve better pain relief effeet and higher level quality of life,can be used in the treatment of castrate -resistant prostate cancer with bone metastasis.
作者
黄智峰
雷金娣
吴松
钟喨
刘毅豪
郑东翔
唐荣志
HUANG Zhifeng;LEI Jindi;WU Son;ZHONG Liang;LIU Yihao;ZHENG Dongxiang;TANG Rongzhi(Department of Urology,Zhongshan Hospital Affiliated of Guangzhou University of Traditional Chinese Medicine,Zhongshan 528400,China)
出处
《中国民族民间医药》
2019年第1期92-95,共4页
Chinese Journal of Ethnomedicine and Ethnopharmacy
关键词
前列腺癌
骨转移疼痛
耳穴
唑来膦酸
Prostate Cancer
Bone Metastasis
Auricular Point Sticking
Zoledronic Acid
