摘要
目的探讨规律腹膜透析改血液透析的患者更改透析模式前后多指标及并发症差异,以指导患者适应透析方式的改变。方法回顾性分析广州市花都区人民医院肾内科2009年1月25日至2017年1月25日因各种原因规律腹膜透析失败改血液透析且资料完整的患者(26例),选取患者更改模式前最后一次检验结果及进入血液透析3个月后的检验结果。使用SPSS19.0进行统计分析。结果腹膜透析转血液透析组男性患者16例,女性10例,年龄(53.46±16.49)岁,更改透析模式后与更改透析模式前相比,总蛋白水平高,[(69.06±8.86)g/Lvs.(61.91±9.60)g/L,P<0.05],白蛋白水平升高[(37.25±4.60)g/Lvs.(32.31±6.87)g/L,P<0.05],血磷水平升高[(2.38±0.95)mmol/Lvs.(1.82±0.72)mmol/L,P<0.05],血钾水平升高[(5.28±0.90)mmol/Lvs.(4.08±1.08)mmol/L,P<0.05],尿素氮水平降低[(19.12±9.72)mmol/Lvs.(27.12±9.10)mmol/L,P<0.05],肌酐水平降低[(888.45±25.23)μmol/Lvs.(1022.64±37.85)μmol/L,P<0.05],总胆固醇水平降低[(3.78±0.83)mmol/Lvs.(4.52±0.98)mmol/L,P<0.05]。患者在白细胞、血红蛋白、血钙、甘油三酯、血钠、超敏C反应蛋白、肾小球滤过率、血清铁、总铁结合力、转铁蛋白饱和度比较差异均无统计学意义。结论两种透析方式均可作为肾脏替代治疗的方式,原腹膜透析患者转血液透析的过渡阶段需加强宣教,避免高钾血症的发生。
Objective To investigate the difference in the indicators and the complications of end stage renal disease of patients before and after changing peritoneal dialysis into hemodialysis, in order to guide the patients to adapt new dialysis methods. Methods Retrospectively analysis of 26 patients who changed dialysis mode with? complete clinical date during January 2009 to January 2017 in the hospital was performed, the last results before change mode and 3 months after changing to hemodialysis were selected. SPSS 19.0 software was used to analyze the data. Results There were 16 males and 10 females patients, mean age was (53.46 ±16.49)years. After changing to hemodialysis dialysis, the total protein level was higher[(69.06±8.86)g/L vs. (61.91±9.60)g/L, P<0.05], albumin level was higher[(37.25±4.60)g/L vs. (32.31±6.87)g/L, P<0.05], phosphorus level was higher[(2.38±0.95) mmol/L vs. (1.82±0.72) mmol/L, P<0.05], potassium level increased significantly[(5.28±0.9) mmol/L vs.(4.08±1.08) mmol/L, P<0.05], urea nitrogen, serum creatinine and total cholesterol decreased significantly[(19.12±9.72) mmol/L vs. (27.12±9.10)mmol/L, P<0.05], [(888.45±25.23)μmol/L vs. (1022.64±37.85)μmol/L, P<0.05], [(3.78±0.83) mmol/L vs. (4.52±0.98)mmol/L, P<0.05]. The changes in leukocyte, hemoglobin, serum calcium, triglyceride, serum sodium, high-sensitivity C-reactive protein, estimated glomerular filtration rate, serum iron, total iron binding capacity, transferin saturation were not statistically significant (P<0.05). Conclusions Both peritoneal dialysis and hemodialysis can be used as a replacement for end stage renal disease patients. In the transitional phase, we should strengthen education carefully for the patients to avoid the occurrence of hyperkalemia.
作者
赵世莉
罗杰
张云芳
田鲁
李红艳
Zhao Shili;Luo Jie;Zhang Yunfang;Tian Lu;Li Hongyan(Department of Nephrology,People's Hospital of Huadu District,Guangzhou 510800,China)
出处
《国际泌尿系统杂志》
2019年第1期109-112,共4页
International Journal of Urology and Nephrology
基金
广东省自然基金(2016A030313420)
广东省科技计划项目[粤科规财(2015)110号0024]
广州市科创委项目(201804010066)
广州市医学重点学科建设项目(2017-2020)
广州市花都区科技与信息局(16-HDWS-32).
关键词
肾透析
腹膜透析
肾替代疗法
Renal Dialysis
Peritoneal Dialysis
Renal Replacement Therapy
