摘要
目的探讨不同分娩间隔时间对高龄经产妇的妊娠结局的影响。方法 2016年1月1日至2016年12月31日本院收治的足月阴道试产的高龄单胎妊娠的经产妇共222例,其中10例转行剖宫产。根据分娩间隔时间分为三组:A组(1～3年)、B组(4～6年)、C组(7～9年)和D组(≥10年),对比分析各组经产妇临床特点、妊娠期并发症、母胎结局和产程时间。结果四组的年龄比较差异有统计学意义(P <0. 01),但四组高龄经产妇产程中缩宫素使用率(P=0. 465)、娠期糖尿病(P=0. 698)、妊娠期高血压疾病(P=0. 158)、胎膜早破(P=0. 542)和产后出血(P=0. 124)的发生率差异无统计学意义。在212例经阴道分娩的高龄经产妇中,A组第一产程时间为(239. 16±137. 63) min,较B组[(296. 36±124. 56) min]、C组[(332. 81±181. 01) min]和D组[(337. 19±224. 02) min]所需时间短(P=0. 030),但第二产程(P=0. 137)和第三产程(P=0. 079)时间差异无统计学意义。新生儿出生体重(P=0. 276)、新生儿性别(P=0. 918)和新生儿重症监护室转科率(P=0. 103)比较差异均无统计学意义,但A组和D组新生儿窒息率明显高于B、C组(P=0. 021)。结论在高龄经产妇中,随着分娩间隔时间延长,第一产程所需时间随之增加,但不影响第二及第三产程时间。分娩间隔时间为1～3年和≥10年的新生儿窒息率明显增高。
Objective To investigate obstetric outcomes of muhiparous pregnancies with advanced maternal age in different inter-pregnancy intervals.Methods A retrospective study was performed in 222 multiparous pregnancies with advanced maternal age from January 1 st 2016 to December 31st 2016.According to the inter-pregnancy intervals,all cases were divided into four groups:Group A (1 -3 years),group B (4 -6 years)group C (7 -9 years)and group D (≥10 years).The clinical characteristics,complications during pregnancy,maternal and fetal outcomes and duration of labor were compared and analyzed in the four groups.Results The average age of groups was significantly different (P <0.001 ).But there was no significant difference in the rate of oxytocin (P =0.465 ),incidence of gestational diabetes mellitus (P =0.698 ),pregnancy-induced hypertension (P =0.158),premature rupture of membrane (P =0.542) and postpartum hermorrhege (P =0.124)among the four groups.A total of 212 pregnancies underwent vaginal delivery.In group A,the first stage of labor last (239.16 ±137.63)min,which was significantly shorted than that in group B [(296.36 ±124.56 )min ],group C [(332.81 ±181.01 )min]and group D [(337.19 ±224.02)min,P =0.0301.However,the interval of delivery did not prolong the second (P = 0.137)and third stage of labor (P =0.079).The neonatal birth weight (P =0.276)and the neonatal sex (P =0.918 ),as well as admission of neonatal intensive care unit (NICU,P =0.103 ),were similar among three groups.The rate of neonatal asphyxia in group A and group D was higher than that in group B and group C (P =0.021 ).Conehlsions Although the second and third stage were similar among multiparous pregnancies with advanced maternal age,the first stage of labor last longer in the longer inter-pregnancy interval.Furthermore,the risk of neonatal asphyxia was higher in women with inter-pregnancy interval ≤3 years or ≥10 years.
作者
祝彩霞
熊玮
王马列
杨娟
王子莲
Zhu Caixia;Xiong Wei;Wang Malie;Yang Juan;Wang Zilian(Department of Obstetrics and Gynecology,The First Affiliated Hospital,Sun Yat-sen University,Guangzhou 510080,China;Department of Anesthesiology,The First Affiliated Hospital,Sun Yat-sen University,Guangzhou 510080,China)
出处
《中国医师杂志》
CAS
2019年第1期73-75,80,共4页
Journal of Chinese Physician
关键词
生育间隔
产次
母亲年龄
妊娠结局
Birth intervals
Parity
Maternal age
Pregnancy outcome
