摘要
为探讨内镜黏膜下剥离术(ESD)治疗结直肠癌及癌前病变术后延迟性出血的危险因素,回顾我院2015年10月至2017年3月收治的行ESD治疗并经术后病理证实为早期结直肠癌及癌前病变的102例患者资料,根据是否发生延迟性出血分组,未发生延迟性出血者为对照组,发生延迟性出血者为观察组。采用单因素及多因素分析引起延迟性出血的危险因素。结果显示,102例早期结直肠癌及癌前病变者术后发生延迟性出血9例(8.82%)。2组患者在病灶位置、病理特点、病灶纤维化程度、术中有无明显出血及是否熟练手术方面比较差异均有统计学意义,P <0.05。病灶位于直肠及病灶黏膜下层重度纤维化是早期结直肠癌及癌前病变ESD术后发生延迟性出血的独立危险因素。结果表明,病灶位于直肠及病灶黏膜下层重度纤维化的早期结直肠癌及癌前病变患者ESD术后易发生迟发性出血。
In order to explore the risk factors of delayed bleeding (DB)following endoscopic submucosal dissection(ESD)for early colorectal carcinoma and precancerous lesion,author retrospectively analysed the data of 102 cases who were admitted and received surgical treatment in author's hospital(2015-10-2017-03),secondaryly were confirmed having early colorectal carcinoma and precancerous lesions,among whom the patients without DB as control group,meanwhile the patients with DB as observation one,their DB risk factors were statistically analyzed.As results,after surgery 9 cases had DB (9/102,8.82%),what's more in lesion location,pathological features,fibrosis degree of lesion,with or without intraoperative distinct bleeding,and whether or not skillful manipulation there was significant difference between the two groups(P<0.05);the lesion located at rectum and its submucosal,severe fibrosis were considered as the risk factors resulting in DB.Results show that the lesion located at rectum and its submucosal severe fibrosis for early colorectal carcinoma and precancerous lesion easily induce Patients'DB。
作者
吴成甫
WU Cheng-fu(Dept.of Endoscopy ,the Second People's Hospital of Nanyang City ,Nanyang ,Henan 473012)
出处
《中国肛肠病杂志》
2018年第11期14-16,共3页
Chinese Journal of Coloproctology
关键词
早期结直肠癌
癌前病变
内镜黏膜下剥离术
术后
迟发性出血
危险因素
Early colorectal carcinoma
Precancerous lesion
Endoscopic submucosal dissection
Postoperation
Delayed bleeding
Risk factor
