摘要
目的研究对比罗哌卡因与利多卡因神经阻滞治疗枕神经痛的临床疗效,为临床枕神经痛的药物治疗提供参考。方法 2014年1月-2017年6月期间收治的枕神经痛患者90例为研究对象,按随机数字表法分为观察组和对照组,每组患者45例。观察组患者采用罗哌卡因神经阻滞治疗,对照组采用利多卡因神经阻滞治疗。于治疗后对两组患者的临床疗效进行评价比较,并采用视觉模拟评分法(VAS)对两组患者治疗前后的疼痛程度进行评分比较,期间对两组患者治疗过程中出现的不良反应的种类和发生率进行比较。结果 (1)观察组患者治疗的总有效率为95.56%(43/45),对照组的总有效率为80.00%(36/45),组间比较差异有统计学意义(P <0.05)。(2)观察组患者在治疗后1、3、6个月的VAS评分均低于对照组患者,组间比较差异有统计学意义(P <0.05)。(3)观察组患者的不良反应发生率为13.33%(6/45),对照组不良反应发生率为11.11%(5/45),组间比较差异无统计学意义(P> 0.05)。结论相比于利多卡因神经阻滞治疗,对于枕神经痛患者采用罗哌卡因神经阻滞可获得更好的临床疗效,缓解患者的疼痛效果明显,且不良反应少,用药安全性好,有较高的临床应用价值,值得进一步推广应用。
Objective To compare the clinical efficacy of ropivacaine and lidocaine to nerve block in the treatment of occipital neuralgia, so as to provide references for clinical treatment of occipital neuralgia. Methods 90 patients with occipital neuralgia admitted to our hospital from January 2014 to June 2017 were selected as the subjects. They were randomly divided into the observation group and the control group, with 45 cases in each group. The patients in the observation group were blocked nerve with ropivacaine and, while the control group was treated with lidocaine. After treatment, the clinical curative effect of two groups were evaluated and compared by using visual analogue scale(VAS). Degree of pain in two groups before and after treatment was assessed. The types and incidence of adverse reactions occurred in two groups of patients during treatment were compared. Results(1)The total effective rate of the observation group was 95.56%(43/45), while the total effective rate of the control group was 80%(36/45), and the difference between two groups was statistically significant(P < 0.05). The VAS scores of the patients in the observation group were lower than those in the control group at 1,3 and 6 months after treatment, and there was a significant difference between the groups(P < 0.05).(3) The incidence of adverse reactions in the observation group was 13.33%(6/45), and the incidence of adverse reactions in the control group was 11.11%(5/45).There was no significant difference between two groups(P > 0.05). Conclusions Compared to the treatment of nerve block of lidocaine,ropivacaine can obtain better patients with occipital neuralgia. It can relieve the pain of the patients with obvious effect, and it has less adverse reactions, more drug safety and higher clinical value. So it is worthy of further application.
作者
王晶
WANG Jing(Hospital of the Sixth Agrieultural Division,Xinjiang,Wujiaqu city,831300,China)
出处
《新疆医学》
2018年第10期1076-1078,共3页
Xinjiang Medical Journal
