摘要
降血脂多糖活性显著、来源众多且安全性高,应用前景广阔。该文根据降血脂活性多糖的结构特征将其分为多糖硫酸酯、氨基多糖、同多糖和杂多糖4类,简要综述了近年关于4类多糖的降血脂活性机制研究和构效关系假设,以期为降血脂多糖的研究及产品开发提供参考。
Hypolipidemic polysaccharides have notable activity and safety with a range of diverse sources. In this paper,the classification of hypolipidemic polysaccharides was carried out into polysaccharide sulfate,glycosaminoglycan,homopolysaccharide and heteropolysaccharide. The hypolipidemic activity mechanism and structure-activity relationship hypothesis of those polysaccharides in recent years were briefly reviewed therefore to provide references for the study and product development of polysaccharides.
作者
杨夏
冯颖淑
童珊珊
余江南
徐希明
YANG Xia;FENG Ying-shu;TONG Shan-shan;YU Jiang-nan;XU Xi-ming(School of Pharmacy,Jiangsu University,Zhenjiang 212013,China)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2018年第20期4011-4018,共8页
China Journal of Chinese Materia Medica
基金
国家自然科学基金项目(81273470,81473172,81503025)
关键词
多糖
降血脂
活性机制
构效关系
polysaccharides
hypolipidemic
activity-mechanism
structure-activity relationship
