摘要
目的:研究四逆火灸疗法治疗阳虚型消化道肿瘤患者癌因性疲乏的临床疗效。方法:筛选2017年1月至2018年1月我科收治的阳虚型消化道肿瘤患者120例,随机平均分为火疗组和常规组。常规组和火疗组均进行抗癌及营养支持等基础治疗,常规组在基础治疗上增加艾灸法,火疗组增加"四逆火灸"疗法,疗程为1个月。评估指标两组患者的Piper疲乏量表及分级、生存质量、阳虚症状评分、临床疗效及化疗患者的血常规指标。结果:治疗后火疗组疲乏程度低于常规组,差异有统计学意义(χ2=4.24,P=0.037 <0.05),火疗组生活质量总量表和5个子量表的评分改善值高于常规组,差异有统计学意义(P <0.01),火疗组生活阳虚体质评分改善值大于常规组,差异有统计学意义(P <0.01),火疗组疲乏,恶心呕吐,失眠,纳差,腹泻的评分改善值高于常规组,差异有统计学意义(P <0.05或P <0.01)。火疗组总有效率为76.67%高于常规组91.53%,差异有统计学意义(χ2=5.64,P=0.012<0.01),火疗组化疗患者的血红蛋白改善值3.92±1.18高于常规组1.02±0.52,差异有统计学意义(t=7.212,P=0.003<0.01)。结论:四逆火灸能改善阳虚型消化道肿瘤患者的疲乏程度,减少阳虚的不适症状,提高生活质量,并能提升化疗患者血红蛋白含量。
Objective: To study the clinical efficacy of Sini-Moxibustion in the treatment of cancer-induced fatigue in patients with yang-deficiency gastrointestinal cancer. Methods: A total of 120 patients with gastrointestinal cancer treated in our department from January 2017 to January 2018 were randomly divided into 2 groups: the fire moxibustion group and the conventional group. The conventional group and the fire therapy group were treated with basic treatments such as anti-cancer and nutritional support. The conventional group added Sini-Moxibustion to the basic treatment, and the fire therapy group added"Sini-Moxibustion"therapy for a period of 1 month. Tthe indicators of the 2 groups of patients with Piper fatigue scale and grade, quality of life, symptoms of yang deficiency symptoms, clinical efficacy and blood tests of patients with chemotherapy were evaluated. Results: After the treatment, the degrees of fatigue in the fire moxibustion group was lower than that in the conventional group with statistically significant difference( χ^2= 4.24, P =0.037 < 0.05). The scores of improvement in the quality of life scale and five subscales in the fire moxibustion were higher than those in the conventional group with statistically significant difference(P < 0.01), and the improvement score of the body yang deficiency in the fire moxibustion group was greater than that of the conventional group(P < 0.01). The scores of fatigue, nausea and vomiting, insomnia, anorexia, and diarrhea in the fire moxibustion group were higher than those in the conventional group with statistically significant difference(P < 0.05 or P < 0.01). After treatment, the total effective rate was 76.67% in the fire moxibustion treatment group, which was higher than the conventional group 91.53%with statistically significant difference( χ^2= 5.64, P = 0.012 < 0.01). Hemoglobin improvement value of 3.92 ± 1.18 in the fire moxibustion group was higher than that of the conventional group 1.02 ± 0.52 with statistically significant difference(t = 7.212, P = 0.003 < 0.01). Conclusion: Sini-moxibustion can improve the CRF of patients with yangdeficiency gastrointestinal cancer, reduce the symptoms of yang deficiency, improve the quality of life, and increase the hemoglobin content in patients with chemotherapy.
作者
徐静艳
谢寅飞
陆伟慧
盛颖玥
魏小丽
李成
Xu Jingyan;Xie Yanfei;Lu Weihui;Sheng Yingyue;Wei Xiaoli;Li Cheng(Department of Acupuncture,The Third People's Hospital of Wuxi,Wuxi 214041,China;Gastroenterology Department,The Third People's Hospital of Wuxi,Wuxi 214041,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2018年第11期2045-2050,共6页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
无锡市卫生和计划生育委员会"科教强卫"青年人才项目(QNRC096):6-姜酚调节Th17/Treg细胞平衡干预溃疡性结肠炎的机制研究
负责人:盛颖玥
关键词
阳虚
消化道肿瘤
癌因性疲乏
四逆火灸
Yang deficiency
gastrointestinal cancer
cancer-induced fatigue
fire moxibustion with Sini decoction
