摘要
目的:观察理肺汤联合穴位埋线治疗慢性阻塞性肺疾病(COPD)合并肺动脉高压(PH)稳定期的临床疗效。方法:将纳入的64例COPD合并PH患者随机分为观察组与对照组各32例。对照组给予平喘止痉等对症治疗,观察组在对照组基础上加用理肺汤和穴位埋线疗法治疗。观察2组治疗前后6 min步行距离、COPD评估测试(CAT)评分、肺动脉收缩压(PASP)及中医证候积分的变化,评估临床疗效,记录治疗前后的急性发作次数。结果:治疗后,2组6 min步行距离均较治疗前增加(P <0.05),观察组6 min步行距离长于对照组(P <0.05)。治疗后,2组CAT评分及中医证候积分均较治疗前降低(P <0.05),观察组CAT评分及中医证候积分均低于对照组(P <0.05)。治疗后,观察组PASP较治疗前降低(P <0.05);对照组PASP与治疗前比较无差异(P> 0.05);观察组PASP低于对照组(P <0.05)。观察组总有效率96.88%,对照组总有效率71.88%,2组比较,差异有统计学意义(P <0.05)。治疗后,观察组急性发作次数较治疗前减少(P <0.05);对照组急性发作次数与治疗前比较差异无统计学意义(P> 0.05);观察组急性发作次数少于对照组(P <0.05)。结论:在西医治疗基础上联合理肺汤和穴位埋线疗法治疗COPD合并PH稳定期,可有效改善患者的临床症状,降低PASP,延缓病情进展。
Objective:To observe the clinical effect of Lifei tang combined with acupoint catgut-embedding therapy for chronic obstructive pulmonary disease(COPD)complicated with pulmonary hypertension(PH)in the stable stage.Methods:Divided 64 cases of patients with COPD and PH into the observation group and the control group randomly,32 cases in each group.The control group was given such treatments as for relieving asthma and arresting spasm,while the observation group was additionally given Lifei tang combined with acupoint catgut-embedding therapy.Observed the changes of distance of6-min walk,scores of COPD assessment test(CAT),pulmonary artery systolic pressure(PASP)and Chinese medicine syndrome scores in both groups before and after treatment,evaluated the clinical effect,and recorded the frequency of acute attacks before and after treatment.Results:After treatment,the distance of 6-min walk in both groups was longer than that before treatment(P<0.05),and the distance of 6-min walk in the observation group was longer than that in the control group(P<0.05).After treatment,CAT scores and Chinese medicine syndrome scores in both groups were lower than those before treatment(P<0.05),and CAT scores and Chinese medicine syndrome scores in the observation group were lower than those in the control group(P<0.05).After treatment,the level of PASP in the observation group was lower than that before treatment(P<0.05);there was no significant difference being found in the level of PASP of the control group when comparing with that before treatment(P>0.05);the level of PASP in the observation group was lower than that in thecontrol group(P<0.05).The total effective rate was 96.88%in the observation group and 71.88%in the control group,difference being significant(P<0.05).After treatment,the frequency of acute attacks in the observation group was less than that before treatment(P<0.05);there was no significant difference being found in the frequency of acute attacks in the control group when comparing with that before treatment(P>0.05);the frequency of acute attacks in the observation group was less than that in the control group(P<0.05).Conclusion:The application of Lifei tang combined with acupoint catgut-embedding therapy for COPD complicated with PH in the stable stage on the basis of western medicine therapy can effectively improve the clinical symptoms of patients,reduce the level of PASP and delay the progression of disease.
作者
区淑娟
路向东
郭常庆
OU Shujuan;LU Xiangdong;GUO Changqing
出处
《新中医》
CAS
2019年第1期205-209,共5页
New Chinese Medicine
基金
庆阳市2016年科技支撑项目(KZ2016-45)
