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非甾体抗炎药致上消化道出血的经济负担研究 被引量:12

Economic burden due to nonsteroidal anti-inflammatory drugs-induced upper gastrointestinal bleeding
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摘要 目的 研究上消化道出血住院病人中服用非甾体抗炎药 (NSAIDs)的比例以及NSAIDs引起的上消化道出血的经济负担。方法  4个中心记录所有上消化道出血住院病人及其医疗费用。结果  36 9例上消化道出血住院病人中有 16 5 %在出血前 10d内服用过NSAIDs,服用的NSAIDs品种以乙酰氨基芬、阿司匹林、双氯芬酸及克感敏为主 ,3/ 4的病人服用NSAIDs的时间少于10d。消化道出血病人平均住院 13d ,住院费用平均为 4143元 ,住院前门急诊费用为 112 4元 ,其他非医疗的直接费用约为 180 8元。结论 NSAIDs引起的严重不良反应值得关注 。 Objective To study the proportion of patients taking nonsteroidal anti inflammatory drugs (NSAIDs) in inpatients with upper gastrointestinal (GI) bleeding and the economic burden of NSAIDs induced upper GI bleeding.Method All 369 inpatients with upper GI bleeding in 4 centers were recorded and investigated.Results Of these inpatients with upper GI bleeding,16 5% took one or more NSAIDs in 10 days before bleeding occurrence.Acetaminophen,aspirin,diclofenac and chlorphenamine composite were the leading NSAIDs.Every inpatient with NSAIDs induced GI bleeding hospitalized by an average of 13 days and cost 4 143 RMB yuan,1 124 yuan for emergency befor hospitalization and 1 808 yuan for nonmedical expense.Conclusion More attention should be put on NSAIDs induced GI complications.Proper measures can be employed to significantly decrease the occurrence and economic burden of NSAIDs induced GI complications.
出处 《中华风湿病学杂志》 CAS CSCD 2002年第1期31-34,共4页 Chinese Journal of Rheumatology
关键词 非甾体消炎药 上消化道出血 费用效益分析 药物不良反应 经济负担 NSAIDS Anti inflammatory agents,non steroid Gastrointestinal hemorrhage Cost benefit analysis Economics,medical
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