摘要
原发性局灶节段性肾小球硬化(pFSGS)是肾脏病领域中常见的疑难疾病 ,可表现为肾病综合征、慢性肾炎、隐匿性肾炎。综合临床宏观和微观辨证所见 ,pFSGS的中心证候是肾虚血瘀 ;肾虚以气阴两虚为主 ,血瘀普遍存在于 pFSGS患者中 ,故提出益肾消为主中西医结合治疗 pFSGS。临床上以益肾方(黄芪、制何首乌、金樱子等组成)和消方(积雪草、桃仁、制大黄等组成)为主 ,配合强的松、环磷酰胺、血管紧张素转换酶抑制剂 ,或雷公藤多甙片等治疗30例 ,结果缓解16例(53 33%) ,显效8例(26 67%) ,有效5例(16 6 %) ,无效1例(3 33 %) ,缓解 +显效率达80 % 。
The primary focal sectional glomerular sclerosis(pFSGS)is a common refractory disease,which can be manifested as nephritic syndrome,chronic nephritis and potential nephritis seen from the clinical macroscopic and microscopic differentiation of symptoms and signs,the main symptoms of pFSGS are kidney mufficiency and blood stasis.Kidney is mainly mufficient in qi and yin,blood stasis is popular among pFSGS patients.So it's suggested to treat pFSGS by combining TCM and WM with emphasis on tonifying kidney and removing masses.Here 30 cases were treated by Yishen Fang(milkvetch root,prepared fleece flower root,Cherokee rose hip,etc.)and Xiaozheng Fang(centella,peach kernal and prepared Rheum officinale Baill,etc.)combining Qiangdisong cyclophosphamide,angiotensin invertase inhibitant or tripterygium wilfordii polyglycoside tablets etc..The result showed that 16 cases were alleviated(53 33%);8,had marked effect(26 67%);5,had effect(16 6%);1,had no effect(3 33%);the rate of alleviation+marked effect reached 80%.It's worth of further study and more examination.
出处
《浙江中医学院学报》
2002年第1期19-21,共3页
Journal of Zhejiang College of Traditional Chinese Medicine
