摘要
本文应用放免法测定了正常人16例、肺气肿13例、肺心病51例血浆心钠素(ANP)、肾素活性(PRA)、血管紧张素Ⅱ(AT Ⅱ)、醛固酮(Aldo)的浓度,结果发现①肺气肿组血浆 ANP 水平明显低于正常对照组;②肺心病不同心功能血浆 ANP 水平不同,心功能Ⅰ、Ⅱ、Ⅲ级肺心病患者的血浆 ANP 浓度各组之间有明显差异;③肺心病组血浆 PRA,AT Ⅱ、Aldo 的水平明显高于肺气肿组;④血浆 ANP 与 PRA 有一定的正相关。
Plasma levels of atrial natriuretic peptide(ANP),renin(PRA),angiotensin(AT2)and aldosterone(Aldo)were determined in 13 patients with pulmonary emphy-sema,51 patients with cor pulmonale and 16 normal Controls with radioimmunoassay.The results showed that:(1)Plasma levels of ANP in pulmonary emphysema groupwas significantly lower than that in the control group;(2)Plasma ANP values va-ried with the severity of cor pulmonale.There were very significant differences amongthese groups;(3)Plasma PRA,AT2,Aldo levels were markedly higher in cor Pul-monale group than those in pulmonary emphysema group;(4)There was a positivecorrelation between ANP and PRA.
出处
《天津医药》
CAS
1991年第11期643-646,共4页
Tianjin Medical Journal
关键词
心钠素
肾素
阻塞性肺病
肺心病
atrial natriuretic polypeptide
renin
angiotensin 2
aldosterone chronic obstructive pulmonary disease cor Pulmonale
