摘要
[目的 ]探讨腺苷三磷酸 氯化镁加常规抗癌药物局部动脉灌注对晚期恶性肿瘤疗效的影响 .[方法 ]将对象分为实验 (给予化学疗法药物加腺苷三磷酸 氯化镁 )组和对照 (给予单纯化学疗法药物 )组 ,进行动脉灌注治疗 ,并对比 2组的临床疗效及副反应 .[结果 ]实验组 4 0例晚期恶性肿瘤病例中完全缓解 5例 ,部分缓解 8例 ,微效 5例 ,稳定 17例 ,进展 5例 ,有效率为 3 3 % .对照组 3 9例中完全缓解 1例 ,部分缓解 7例 ,微效 11例 ,稳定 14例 ,进展 6例 ,有效率为 2 1% .两组未见明显的毒副反应差异 .[结论 ]腺苷三磷酸 氯化镁可提高抗癌药物的抗癌作用 ,对一些中、晚期恶性肿瘤具有较好的疗效 ,无明显的毒副反应 ,是一种安全、有效的抗肿瘤药物 .
OBJECTIVE?To study the anti cancerous effects of local arterial infusion with ATP MgCl 2 and routine anti cancerous medicines for advanced stage malignant tumor.?METHODS?The clinical curative effects and side effects were compared between experimental group of chemotherapy combined with ATP MgCl 2 and control group of chemotherapy only.?RESULTS?In 40 patients of experimental group, completed response(CR) was observed in 5 cases, patitial response(PR) in 8, minor regression(MR)in 5, stabilized disease(SD)in 17 and progressive disease(PD)in 5, and the rate of overall response was 33%. In 39 patients of control group, CR was observed in 1 case,PR in 7, MR in 11, SD in 14 and PD in 6,and the rate of overall response was 21%. There is no significant side effect difference in two groups.?CONCLUSION?The ATP MgCl 2 could improve the anti cancerous effects of anti cancerous medicine, had preferable curative effects for some advanced malignant tumor and had no obvious side effects, therefore is one kind of safe and effective anti cancerous medicine.
出处
《延边大学医学学报》
CAS
2002年第1期29-32,共4页
Journal of Medical Science Yanbian University
