摘要
以异色满酮 4为起始原料 ,经Claisen缩合得其 β 二酮衍生物 ,再与水合肼进行Knorr反应环合成 3 乙氧甲酰基和 3 肼甲酰基异色满并吡唑衍生物 ,通过酰肼与糠醛反应成腙后 ,分别与巯基乙酸和氯乙酰氯反应合成了标题化合物 .
In this paper, Claisen condensation of isochroman?4?one as starting material with diethyl oxalate is carried out to form β?diketone compound of isochroman?4?one. After Knorr cyclization of hydrazine with hydrazon formed with furfural,the title compounds are synthesized by the cycloaddition with mercaptoacetic acid and chloroacetyl chloride.
出处
《烟台大学学报（自然科学与工程版）》
CAS
2002年第2期113-117,共5页
Journal of Yantai University(Natural Science and Engineering Edition)
