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视网膜下液脂质过氧化物的测定与视网膜脱离关系的研究 被引量:2

A study on relationship between retinal detachment and assaly of lipid peroxidation in subretinal fluid
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摘要 目的 测定孔源性视网膜脱离 (rhegmatogenous retinal detachment,RRD)患者视网膜下液 (subreti-nal fluid,SRF)中过氧化脂质 (lipid peroxidation,L PO)的含量 ,探讨其与 RRD的关系。方法 用硫代巴比妥酸—醋酸法直接比色测定 40例 RRD患者 SRF及血清中 L PO的含量。结果  SRF中含有 L PO,其含量随增生性视网膜玻璃体病变 (proliferative vitreoretinopathy,PVR)和玻璃体混浊程度的加重、病程延长及视网膜脱离范围的增大而增加。结论  RRD患者 SRF中 L PO的含量与 RRD的发生密切相关。 Objective To detect lipid peroxidation(LPO) in the subretinal fluid(SRF) after rhegmatogenous retinal detachment(RRD) and to probe into the relationship between LPO and RRD.Methods LPO were detected directly by thiobarbituric acid-acetic acid colorimetric method respetively in the SRF and blood of 40 patients with RRD.Results We found that SRF contained production of LPO.The level of LPO in the SRF was identified with the degree of pathology of retina and vitreous,with the time and range of RRD(P<0.05).Conclusion The results indicate that the LPO in SRF has a close relation with RRD.
出处 《临床眼科杂志》 2002年第2期106-108,共3页 Journal of Clinical Ophthalmology
关键词 视网膜下液 脂质过氧化物 视网膜脱离 测定 Subretinal fluid Lipid peroxidation Retinal detachment
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