摘要
nAChRs在昆虫的神经系统的兴奋性神经传导中起着极其重要的作用,并且是杀虫剂的一个重要靶标。本文就以下几方面作了详细的阐述:作用于昆虫nAChRs的各类化学杀虫剂的演绎,nAChRs的结构与活性,烟碱类似物的结构与活性,新烟碱类杀虫剂的结构修饰及其选择性,以及新烟碱类的药效基团。
nAChRs play a major role in excitary neurotransmition in insect CNSs and constitute an important target for insecticides. Present paper elucidates the following aspects; evolution of chemical classes of insecticides that act on insect nAChRs, structure and function of nAChRs, structure - activity of nicotine analogs, the structure modified and selectivity of neonicotinoid insecticides, and the pharmacophore of neonicotinoids.
出处
《现代农药》
CAS
2002年第1期1-6,共6页
MODERN AGROCHEMICALS
