摘要
目的 探讨地方性氟中毒与氟以外的有关化学元素的关系,寻找行之有效的抗氟元素。方法 应用病例对照研究的流行病学方法,对地氟病区内外环境中钙、镁、铜、铁、锌、硒、氟等化学元素进行了测定。结果 氟骨症病人血清钙、镁、铜含量较对照组明显降低（P<0.05～0.01）.血清铁水平则升高（P<0.05）:氟病区非氟骨症患者血清钙、镁含量较正常人群减少（P<0.05）;地氟病区粮食、蔬菜中钙、镁、铜含量显示了降低的趋势,尤其是玉米镁含量的降低有显著性差异（P<0.05）。结论 地方性氟中毒与机体内钙、镁、铜、铁等化学元素关系密切,多数表现为拮抗作用。
ve To study the relation between endemic fluorosis and concerned chemical elements and to discover effective antifluoride elements. Methods Calcium(Ca),magnesium(Mg), copper(Cu), iron(Fe),zinc(Zn), selenium(Se) and flu-oride(F) in the environment in the endemic fluorosis area was determined with case-control method. Results Concentration of serum Ca, Mg and Cu decreased obviously in the skeletal fluorosis patients( P < 0.05-0.01), whereas concentration of serum Fe increased significantly; serum Ca and Mg in the no - osteofluorosis patients of the fluorosis area were significantly lower than that of the control group(P<0. 05); Ca, Mg and Cu content in the food and vegetables in the fluorosis area decreased compared with normal area, especially maize Mg content decreased significantly( P < 0.05). Conclusion There were close relation between endemic fluorosis and Ca, Mg, Cu and Fe in body, majority showed anti-action.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2002年第4期433-434,共2页
Chinese Journal of Public Health
