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急性白血病的多药耐药及逆转 被引量:1

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摘要 多药耐药或多药抗性(MDR)系指肿瘤细胞或白血病细胞对结构和作用靶位不同的多种化疗药物有交叉耐药性,为化疗失败主要原因之一.
作者 姚尔固
出处 《河北医药》 CAS 2002年第5期373-374,共2页 Hebei Medical Journal
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  • 1陈慧君,吴绪峰,陈惠祯.TopoⅡα、GST-π、P-gp在卵巢癌化疗耐药中的作用[J].肿瘤防治研究,2006,33(3):197-199. 被引量:13
  • 2周新,涂植光.临床生物化学和生物化学检验.3版.北京:人民卫生出版社,2004:447-470.
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  • 6Hannon GJ. RNA interference. Nature, 2002, 418:244-251.
  • 7Zhang L, Yang N, Mohamed A, et al. Vector-based RNAi, a novel tool for isoform specific knock-down of VEGF and antiangingenesis gene therapy of cancer. Biochem Biophys Res Commun, 2003, 303: 1169.
  • 8Gunn J, McCall JL, Yun K, et al. Detection of micrometastases in colorectal cancer patients by K19 and K20 reverse transcription polymerase chain reaction. Lab Invest, 1996, 75:611-615.
  • 9Fleming TP, Watson MA. Mammaglobin, a breast specific'gene,and its utility as a marker for breast cancer. Annals New Academy Sci, 2000, 923: 78-89.
  • 10Withoff S, De Jong S, De Vries EG, et al. Human DNA Topoisomerase Ⅱ : biochemistry and role in chemotherapy resistance (review). Antieancer Res, 1996, 16: 1867-1880.

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