摘要
目的 :探讨幽门螺杆菌 (HP)感染与血脂、一氧化氮 (NO)水平的关系。方法 :测定心血管疾病患者 192例的血清 HPIg G、总胆固醇 (TC)、甘油三脂 (TG)、载脂蛋白 A1(Apo A1)、载脂蛋白 B(Apo B)、脂蛋白 a[L p(a) ]、高密度脂蛋白胆固醇 (HDL- C)、低密度脂蛋白胆固醇 (L DL- C)、一氧化氮 (NO)、一氧化氮合酶 (NOS)的含量。结果 :HP感染10 8例 ,HP感染组的血清 TG,Apo B,NOs,NO浓度较未感染组明显升高 (P<0 .0 5 ) ,TC,L p(a) ,L DL- C有增高趋势 ,但未达显著水平 .结论 :HP感染可明显升高血清 TG,Apo B,NOS,NO的含量。
AIM:To determine the relation of helicobacter pylori(HP) infection with the levels of lipids and nitric oxide(NO). METHODS:Serum specific IgG antibodies to HP(HPIgG) and serum levels of total cholesterol(TC), triglyceride (TG),apolipoprotein A1(ApoA1),apolipoprotein B(ApoB), apolipoprotein(a),high density apolipoprotein cholesterol(HDL-C),Low density apolipoprotein cholesterol(LDL-C),NO and nitric oxide synthase(NOS) were measured in 192 patients with cardiovascular diseases. RESULTS:108 patients were infected by HP. The levels of serum TG,ApoB,NO,NOS in the cases of HP seropositivity were significantly higher than those in the cases of HP seronegativity (P<0.05). The levels of TC,Lp(a),LDL-C,tended to be higher in those who were HP positive than in those who were HP negative,but the trend was non-significant.CONCLUSION:HP infection might increasethe lipids and NO.
出处
《心脏杂志》
CAS
2002年第2期134-135,138,共3页
Chinese Heart Journal
关键词
心血管疾病
幽门螺杆菌
螺杆菌感染
血脂
一氧化氮
cardiovascular diseases
helicobacter pylori
helicobacter infections
lipid
nitric oxide
