摘要
目的 了解门诊精神分裂症患者精神药物利用情况与治疗依从性关系。方法 随机选择门诊精神分裂症患者 552例 ,由调查者询问并填写自制的精神药物使用调查表。结果 552例精神分裂症患者中使用单一抗精神病药物 (APD)治疗者 1 2 2例占 2 2 1 0 % ;常用的APD中前 3位依次为氯丙嗪、氯氮平和奋乃静 ;APD治疗方案中最常用的为氯丙嗪、氯氮平及氯丙嗪与氯氮平合用 ;患者服用的药物剂量与其治疗依从性间有相关关系 (P <0 0 1 ) ;患者用药种类不同 ,其治疗依从性间的差别有显著性意义 (P <0 0 1 ) ;药物副反应程度与患者治疗依从性间有相关关系 (P <0 0 1 )。结论 简化治疗方案 。
Objective To investigate the relation between utilization of antipsychotic drugs and therapeutical compliance in schizophrenic outpatients.Methods Five hundred and fifty-two schizophrenic patients were selected randomly from the outpatient department,a semi-structural questionnaire of using antipsychotic drugs was filled in.Results 122 patients(22 10%) took a kind of antipsychotic drugs.The first three antipsychotic drugs used frequently were chlorpromazine,clozapine and perphenazine.The therapeutical projects used often were chlorpromazine,clozapine and their combination.There were relationships between drug dosage,the degree of side effect and therapeutical compliance of the Patients(P<0 01).Comparing therapeutical compliance of different drugs,there was significant difference(P<0 01).Conclusion It suggests that therapeutical method should be simplified and the less side-effect drugs be selected,thus it is an effective pathway of improving compliance of therapy.
出处
《中国全科医学》
CAS
CSCD
2002年第5期358-359,共2页
Chinese General Practice
关键词
精神分裂症
药物利用
依从性
治疗
Schizophrenia Utilization of antipsychotic drug Compliance
