摘要
概述了Ru催化的碳氢键的活化反应 ,包括C—H/烯烃 ,C—H/炔烃和C—H/CO/烯烃偶联反应 ,加氢酰化反应 。
In the last few years, much has been learned about the transition metal-catalyzed activation of arylic or olefinic C-H bonds. An important extension of these reactions such as C-H/olefin, C-H/acetylene, C-H/CO and C-H/CO/olefin couplings, hydroacylation and silylation can be regarded as practical tools, for these reactions exhibit high selectivity, high efficiency and wide applicability. Especially the C-H/CO/olefin coupling protocol can be a useful complementary method to Friedel-Crafts reaction, since it takes place even when there're electron-withdrawing groups in the aryl groups of substrates. In these reactions the coordination of the substrates to the ruthenium center in the catalyst complex is a necessary prerequisite for the reactions to proceed. In this paper, we'll survey the Ru-catalyzed functionalizations of C-H bonds that were published up to the end of 2000. These catalytic reactions involve a step of nucleophilic addition by a ruthenium complex. The factors affecting the selectivity shown by different catalysts are also discussed.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2002年第5期307-317,共11页
Chinese Journal of Organic Chemistry
基金
上海市优秀学科带头人资助项目
