摘要
目的 :探讨结肠粘膜重建尿道的可能性。方法 :选择 6条雌性杂种成年犬 ,在全麻下切开尿道 ,剥离全段尿道粘膜 ,取相等长度的结肠粘膜替代尿道粘膜 ,1 2周后将犬处死 ,取其尿道作病理检查。结果 :犬尿道病理组织学检查示移植于尿道的结肠粘膜全部成活 ,大部分腺上皮已转变为移行上皮。结论 :应用结肠粘膜重建尿道是一种新的方法 。
Purpose: To explore the possibility of urethral reconstruction with a free graft of colic mucosa.Methods:Six dogs underwent a procedure in which the urethral mucosa was totally removed and replaced with a free graft of colic mucosa. All dogs were sacrificed 12 weeks after the operation for histological examination of urethra.Results:Histological examination revealed that all of the grafted colic mucosa survived in the urethra of dogs and partial glandular epithelium has been transformed into urethelium.Conclusions:Urethral reconstruction with colic mucosa is a novel method and the technique can be used when local or preputial skin and buccal or bladder mucosa are not available.
出处
《临床泌尿外科杂志》
2002年第6期300-301,共2页
Journal of Clinical Urology
基金
上海市卫生局科技发展基金资助课题 (0 0 4 2 9)
关键词
尿道疾病
外科手术
结肠粘膜
尿道重建
实验研究
Urethral diseases/Surgery
Colic mucosa
Urethral reconstruction
Laboratory research
Mutt
