摘要
目的 观察海尔福口服液对砷中毒小鼠的疗效。方法 以健康的小鼠作实验对象 ,随机分为正常对照组、中毒组、治疗组和标准药物 (硒 )治疗组 ;用亚砷酸钠为毒物进行染毒 ,海尔福口服液和硒为药物进行治疗 ,时间 30d。结束时处死动物 ,取血清测定丙二醛 (MDA)、丙氨酸氨基转移酶 (ALT)和谷胱甘肽过氧化物酶 (GSH -Px)。结果 中毒组MDA、ALT明显高于其他 3组 ,而GSH -Px却低于其他 3组。结论 试验结果证明 。
Objective To investigate the curative effect of HAIERFU oral liquid on arsenic poisoned mice.Methods Healthy mice were randomly divided into 4 groups,namely the control group,poisoned group,HAIERFU\|treated group and standard medicine selenium\|treated group.Sodium arsenite was applied to cause arsenic poisoning.HAIERFU oral liquid and selenium were used as the medicine for treatment lasted for 30 days.Methanedicarboxylic aldehyde(MDA),Alanine aminotransferase(ALT)and glutathione peroxidase(GSH\|Px)were determined in mice serum after the animals were sacrificed.Results The MDA and ALT in the poisoned group are significantly higher than those of the other three groups,and GSH\|Px is significantly lower than those of other three groups.Conclusions Results prove the obvious curative effect of HAIERFU oral liquid on arsenic poisoning in mice.
出处
《工业卫生与职业病》
CAS
CSCD
北大核心
2002年第3期153-154,共2页
Industrial Health and Occupational Diseases
关键词
海尔福
砷中毒
小鼠
治疗
疗效
Arsenic poisoning
Mouse
Curative effect
